Results 11 to 20 of about 251,532 (186)

Type 1 interferonopathy presenting as juvenile idiopathic arthritis with interstitial lung disease: report of a new phenotype

Pediatric Rheumatology Online Journal, 2020
Background STING-associated vasculopathy with onset in infancy (SAVI) is a type 1 interferonopathy manifesting as a pulmonary and vascular syndrome resulting from gain-of-function mutations in TMEM173, the gene encoding STING.
S. L. N. Clarke, L. Robertson, G. I. Rice, L. Seabra, T. N. Hilliard, Y. J. Crow, A. V. Ramanan   +6 more
doaj   +2 more sources

‘The current mental health status of children and young people with JIA, and their wider family’: a charity partner collaboration survey

Pediatric Rheumatology Online Journal, 2023
Background This paper presents insight into the scale of mental health concerns for families who have a child or young person with a diagnosis of Juvenile Idiopathic Arthritis (JIA) living in any of the four nations of the United Kingdom (UK).
Polly Livermore, S. Ainsworth, R. Beesley, S. Douglas, E. Earle, D. Wilson, L. Woolley, J. Clinch   +7 more
doaj   +1 more source

What Is Rheumatoid Arthritis?

Journal of the American Medical Association (JAMA), 2022
ABRIDGED PRESCRIBING INFORMATION : ExemptiaTM (Adalimumab) 40 mg /0.8 mL single use pre filled syringe INDICATIONS AND USAGE Moderate to severe Rheumatoid Arthritis (RA), Juvenile Idiopathic Arthritis (JIA): Moderate to severe active polyarticular JIA in
Melanie H Smith, J. Berman
semanticscholar   +1 more source

IL-6 Revisited: From Rheumatoid Arthritis to CAR T Cell Therapy and COVID-19.

Annual Review of Immunology, 2022
The diverse biological activity of interleukin-6 (IL-6) contributes to the maintenance of homeostasis. Emergent infection or tissue injury induces rapid production of IL-6 and activates host defense through augmentation of acute-phase proteins and immune
T. Kishimoto, Sujin Kang
semanticscholar   +1 more source

Definition and Validation of the American College of Rheumatology 2021 Juvenile Arthritis Disease Activity Score Cutoffs for Disease Activity States in Juvenile Idiopathic Arthritis

Arthritis & Rheumatology, 2021
To develop and validate new Juvenile Arthritis Disease Activity Score 10 (JADAS10) and clinical JADAS10 (cJADAS10) cutoffs to separate the states of inactive disease (ID), minimal disease activity (MiDA), moderate disease activity (MoDA), and high ...
C. Trincianti, E. H. P. van Dijkhuizen, A. Alongi, M. Mazzoni, J. Swart, I. Nikishina, P. Lahdenne, L. Rutkowska-Sak, T. Avčin, P. Quartier, V. Panavienė, Y. Uziel, C. Pruunsild, V. Vargova, S. Vilaiyuk, P. Doležalová, S. Ringold, M. Garrone, N. Ruperto, A. Ravelli, A. Consolaro   +20 more
semanticscholar   +1 more source

Consensus statement on blocking the effects of interleukin-6 and in particular by interleukin-6 receptor inhibition in rheumatoid arthritis and other inflammatory conditions

Annals of the Rheumatic Diseases, 2012
Background Since approval of tocilizumab (TCZ) for treatment of rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA), interleukin 6 (IL-6) pathway inhibition was evaluated in trials of TCZ and other agents targeting the IL-6 receptor and ...
J. Smolen, M. Schoels, Norihiro Nishimoto, F. C. Breedveld, G. Burmester, M. Dougados, P. Emery, G. Ferraccioli, C. Gabay, A. Gibofsky, J. Gómez-Reino, Graeme Jones, T. Kvien, M. Murakami, N. Betteridge, Clifton Bingham, Vivian Bykerk, Ernest Choy, B. Combe, Maurizio Cutolo, W. Graninger, Angel Lanas, Emilio Martín-Mola, C. Montecucco, Mikkel Ostergaard, K. Pavelka, A. Rubbert-Roth, N. Sattar, M. Scholte-Voshaar, Yoshiya Tanaka, Michael Trauner, Gabriele Valentini, Kevin L Winthrop, M. de Wit, D. van der Heijde   +34 more
semanticscholar   +1 more source

Features of Cellular and Humoral Immunity Functioning in Patients with Juvenile Rheumatoid Arthritis

Bolʹ, Sustavy, Pozvonočnik, 2015
The objective was to examine the state of cellular and humoral immunity in children with juvenile rheumatoid arthritis. The study involved 48 patients with juvenile rheumatoid arthritis, 24 patients with reactive arthritis and 22 apparently healthy ...
H.A. Pavlyshyn, T.A. Kovalchuk, O.R. Boiarchuk, T.V. Hariian   +3 more
doaj   +1 more source

Factors Associated With Preterm Delivery Among Women With Rheumatoid Arthritis and Women With Juvenile Idiopathic Arthritis

Arthritis care & research, 2019
Pregnant women with inflammatory arthritis may be at increased risk for preterm delivery (PTD), yet it is unclear what drives this risk. This aim of this prospective cohort study of pregnant women with rheumatoid arthritis (RA), juvenile idiopathic ...
Chelsey J. F. Smith, F. Förger, G. Bandoli, C. Chambers   +3 more
semanticscholar   +1 more source

Characteristics of the Onset and Evolution of Juvenile Rheumatoid Arthritis Symptoms during the First Year of its Development

Zdorovʹe Rebenka, 2015
The article presents the data about early symptoms of juvenile rheumatoid arthritis in comparison with the reactive arthritis. Description of the articular syndrome is provided, the incidence of isolated joints affection and radiologic abnormalities in ...
I.S. Lebets, N.O. Panko, O.V. Matviienko, Ye.M. Zaitseva, N.S. Shevchenko   +4 more
doaj   +1 more source

The Influence of Sanatorium-Resort Rehabilitation on the Cytokine Profile and Quality of Life Parameters in Juvenile Rheumatoid Arthritis

Вестник восстановительной медицины, 2021
Aim. To study was to assess the dynamics of cytokine profile indicators and quality of life in patients with juvenile rheumatoid arthritis under the influence of the standard sanatorium-resort rehabilitation complex. Material and methods.
Elena M. Soboleva, Nikolay N. Kaladze
doaj   +1 more source