Results 71 to 80 of about 5,029 (156)

Use of Semaglutide and Tirzepatide in Rheumatic and Musculoskeletal Diseases: Insights on Initiation Patterns and Weight Loss From the Rheumatology Informatics System for Effectiveness Registry

ACR Open Rheumatology, Volume 8, Issue 5, May 2026.
Objective Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) such as semaglutide (SEM) and tirzepatide (TZP) were initially approved for type 2 diabetes management but are increasingly used for weight loss. Limited data exist on real‐world use among patients with rheumatic and musculoskeletal diseases (RMDs).
Nicholas P. McCormick, Cristiano S. Moura, Jingyi Zhang, Emily E. Holladay, Fenglong Xie, Tapan Mehta, Joshua F. Baker, Jeffrey R. Curtis   +7 more
wiley   +1 more source

Anatomy of the sacroiliac joints in children and adolescents by computed tomography

Pediatric Rheumatology Online Journal, 2017
Background Diagnosing sacroiliitis by magnetic resonance imaging (MRI) in children/adolescents can be difficult due to the growth-related changes. This study analyzed the normal osseous anatomy of the sacroiliac joints (SIJ) in a juvenile population ...
Anna Zejden, Anne Grethe Jurik
doaj   +1 more source

Uveitis in patients with oligoarticular juvenile idiopathic arthritis and juvenile spondyloarthritis/enthesitis related arthritis: is there any difference?

Reumatismo, 2023
Juvenile idiopathic arthritis (JIA) is the most common systemic disease causing uveitis in childhood and adolescence.
A. Martins, S. Ganhão, F. Oliveira Pinheiro, C. Granjo Morais, M. Rodrigues, M. Leuzinger-Dias , L. Figueira, I. Brito   +7 more
doaj   +1 more source

Temporal Trends in and Associations With Nonsteroidal Anti‐inflammatory Drug Prescription in Adult and Pediatric Patients With Inflammatory Bowel Disease

Arthritis Care &Research, Volume 78, Issue 4, Page 439-448, April 2026.
Objective Recent inflammatory bowel disease (IBD) treatment guidelines have recommended against nonsteroidal anti‐inflammatory drug (NSAID) use despite prevalent musculoskeletal symptoms and opioid overuse in this population. Given the discordance between changing national guidelines and potential clinical utility, we sought to assess national temporal
Adam S. Mayer, Rui Xiao, Andrew Grossman, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +5 more
wiley   +1 more source

Amicrobial Pustulosis of the Folds Successfully Treated With Apremilast: Report of Two Cases and Review of the Literature

The Journal of Dermatology, Volume 53, Issue 2, Page 339-350, February 2026.
ABSTRACT Amicrobial pustulosis of the folds (APF) is a rare, chronic‐relapsing neutrophilic dermatosis characterized by sterile pustules affecting major and minor skin folds. It predominantly affects women and is frequently associated with autoimmune diseases such as systemic lupus erythematosus, inflammatory bowel disease, and autoimmune thyroiditis ...
Luca Bettolini, Carlo Alberto Maronese, Stefano Bighetti, Giovanni Genovese, Luisa Sarno, Stefano Buffon, Francesca Laura Boggio, Federica Derlino, Angelo Valerio Marzano   +8 more
wiley   +1 more source

Exhaustion‐Resistant CD8 + T Cells in Ankylosing Spondylitis: A Proposed Three‐Axis Model

Immunology, Volume 176, Issue 4, Page 409-420, December 2025.
Exhaustion‐resistant CD8+ T cells may sustain ankylosing spondylitis. A three‐axis model—intermittent T‐cell receptor engagement, IL‐15/CD28 co‐stimulation and maintained metabolic fitness—explains how PD‐1^high CD8+ T cells retain effector function and accumulate from gut to entheses, promoting inflammation and aberrant bone remodelling.
Xuhong Zhang, Lu Jia, Xueni Lin, Lamei Zhou   +3 more
wiley   +1 more source

Agreement Between Self‐Reported Antirheumatic Medications and Pharmaceutical Claims in an Australian Inflammatory Arthritis Cohort

ACR Open Rheumatology, Volume 7, Issue 10, October 2025.
Objective To assess agreement between prescription claims data and self‐reported medication use via longitudinal questionnaires in the Australian Rheumatology Association Database inflammatory arthritis cohort and to identify predictors of discordant self‐reports.
Tom Lynch, Claire Barrett, Rachel Black, Rachelle Buchbinder, Graeme Carroll, Vibhasha Chand, Catherine L. Hill, Marissa Lassere, Sue Lester, Oscar Russell, Premarani Sinnathurai, Lyn March   +11 more
wiley   +1 more source

Innate Lymphoid Cell Phenotypic and Functional Alterations in Patients With Systemic Juvenile Idiopathic Arthritis

Arthritis &Rheumatology, Volume 77, Issue 10, Page 1442-1450, October 2025.
Objective Systemic juvenile idiopathic arthritis (sJIA) is a chronic childhood disease classically attributed to innate immune cell dysregulation. This study aimed to elucidate the role of innate lymphoid cells (ILCs), including natural killer (NK) cells and helper‐ILCs (hILCs), in sJIA during clinically inactive disease (CID) through phenotypic and ...
Linda Quatrini, Cecilia Ciancaglini, Ivan Caiello, Silvia Santopolo, Manuela Pardeo, Valentina Matteo, Elena Loricchio, Donato Amodio, Elena Morrocchi, Giulio Olivieri, Paolo Palma, Antonella Insalaco, Marco Francesco Natale, Arianna De Matteis, Nicola Tumino, Claudia Bracaglia, Paola Vacca, Lorenzo Moretta, Fabrizio De Benedetti, Giusi Prencipe   +19 more
wiley   +1 more source

Biologics and Small‐Molecule Therapies in Netherton Syndrome: A Comprehensive Review

The Journal of Dermatology, Volume 52, Issue 10, Page 1483-1493, October 2025.
ABSTRACT Netherton syndrome (NS) is a rare congenital ichthyosis caused by loss‐of‐function mutations in the SPINK5 gene, leading to defective expression of the serine protease inhibitor LEKTI. Dysregulated epidermal protease activity results in impaired skin barrier function and chronic inflammation, accompanied by complex immune profiles. NS patients
Shin Morizane, Tomoyuki Mukai, Ko Sunagawa, Ken‐ichi Hasui, Anri Morita, Hayato Nomura, Mamoru Ouchida   +6 more
wiley   +1 more source

Limited role of gadolinium to detect active sacroiliitis on MRI in juvenile spondyloarthritis

, 2015
OBJECTIVE: The aim of this study is to determine the added diagnostic value of contrast-enhanced (CE) magnetic resonance imaging (MRI) compared to routine non contrast-enhanced MRI to detect active sacroiliitis in clinically juvenile spondyloarthritis ...
Baraliakos, Xenofon, Verstraete, Koenraad, Jaremko, Jacob, LEUS, ASTRID, Dehoorne, Jo, Jans, Lennart, Herregods, Nele   +6 more
core   +1 more source