Results 161 to 170 of about 313,990 (261)

New information on a juvenile sauropod specimen from the Morrison Formation and the reassessment of its systematic position [PDF]

, 2014
Carballido, José L.
core  

Fluorinated Hypoxia‐Responsive Aza‐BODIPY for NIR‐II FL/19F MR/PA Imaging and Phototherapy of Lung Cancer

Advanced Science, EarlyView.
Fluorinated N‐oxide aza‐BODIPY nanoemulsions integrate fluorination‐driven molecular design with co‐assembly in fluorinated oil for multimodal imaging‐guided phototherapy. The co‐assembly redshifts fluorescence into the NIR‐II window for deep‐tissue imaging and provides a unified 19F signal for background‐free, quantitative MRI.
Anfeng Li, Fang Wang, Mou Jiang, Yu Li, Xin Zhou, Zhong‐Xing Jiang   +5 more
wiley   +1 more source

Effect of Nano-TiO₂ Dioxide on the Hydration Process of Tunnel Construction in Low-Temperature Environments. [PDF]

Nanomaterials (Basel)
Jiao Y, Chen H, Xu S, Fu F, Tao Y, Cui S.   +5 more
europepmc   +1 more source

PRELID1 and VDAC3 Coordinate a Senescence‐Like State in Germinal Center B Cells to Promote IL‐7–Driven Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
Colorectal cancer is characterized by an immunosuppressive microenvironment that limits immunotherapy efficacy. We identify a senescence‐like state in germinal center B cells driven by the PRELID1–VDAC3 axis, which promotes IL‐7 secretion, alleviates CD8+ T‐cell exhaustion, and enhances antitumor immunity. Targeting this pathway improves responsiveness
Yuhan Liao, Huimeng Xu, Xinghua Zhuo, Shupeng Hu, Lanhui Huang, Zhe Hao, Jianxiong Chen, Yulu Wang, Jun Zhou   +8 more
wiley   +1 more source

Automatically Defining Protein Words for Diverse Functional Predictions Based on Attention Analysis of a Protein Language Model

Advanced Science, EarlyView.
Understanding protein sequence–function relationships remains challenging due to poorly defined motifs and limited residue‐level annotations. An annotation‐agnostic framework is introduced that segments protein sequences into “protein words” using attention patterns from protein language models.
Hedi Chen, Jingrui Zhong, Xiaochun Zhang, Jingke Chen, Lin Guo, Xiaoliang Xiong, Xiaonan Zhang, Xiangyu Liu, Bailong Xiao, Boxue Tian   +9 more
wiley   +1 more source

Employment of the Ascending Aortic Volume as a Predictor of Adverse Outcomes in Patients With Bicuspid Aortic Valve Disease. [PDF]

Rev Cardiovasc Med
Li H, Hu Y, Yuan H, Chen T, Zhuang J.
europepmc   +1 more source

A Mitochondria‐Specific Nanomedicine for Synergistic Chemo‐Photothermal Therapy and Immunogenic Activation Against Breast Cancer

Advanced Science, EarlyView.
Peptide dendrimer–based nanoplatform with mitochondria‐targeting capability was developed for synergistic chemo‐photothermal therapy. The system promotes efficient transcytosis, induces mitochondrial dysfunction, triggers immunogenic cell death (ICD), and enhance antitumor immunity by promoting dendritic cell maturation and T‐cell activation, resulting
Min Li, Jiangqi Feng, Junyang Zhuang, Qingguo Zhong, Yanda Li, Yanzhuo Lv, Shaoteng Huang, Xiangyu Huang, Mingbo Zhang, Xiaofeng Cai, Yuxin Wang, Wenping Chen, Zhenyu Duan, Zhou Chen, Kui Luo, Ning Li   +15 more
wiley   +1 more source

Deciphering Roles of Placental Endoplasmic Reticulum Stress in Complicated Pregnancies and Beyond: The Power of Mouse Models. [PDF]

Cells
Yung HW, Yung YN, Burton GJ, Charnock-Jones DS.   +3 more
europepmc   +1 more source

CircRSU1 Activates the hnRNPA1/HIF‐1α/CD24 Signaling Axis, Promoting Stemness Features of Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study reveals circRSU1 with important oncogenic roles in hepatocellular carcinoma (HCC). CircRSU1, highly abundant in HCC, interacts with and stabilizes hnRNPA1 from ubiquitination and degradation. This stabilization facilitates hnRNPA1 binding to the internal ribosome entry site of HIF1A to increase HIF‐1α protein translation.
Shuting Xue, Danduo Wei, Yongzhi Zhao, Jinchang Pan, Hanyuan Zhang, Niya Liu, Jianjuan Zhang, Jiaxin Liu, Jianping Jin, Mu Xiao, Xinhua Feng, Aifu Lin, Lei Zhao, Stephanie Roessler, Junfang Ji   +14 more
wiley   +1 more source

Editorial expression of concern: Role and fate of SP100 protein in response to Rep-dependent nonviral integration system. [PDF]

Appl Microbiol Biotechnol
Xue YY, Wang R, Yue YB, Xue JL, Chen JZ.
europepmc   +1 more source