Results 51 to 60 of about 41,627 (185)

Pharmacokinetics of Intravenous Melatonin in Preschool‐Aged Pediatric Surgical Patients

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Background Melatonin may have several beneficial clinical effects in the perioperative setting. In children, it has been studied for preoperative anxiety, postoperative pain, and emergence delirium. Melatonin's pharmacokinetic profile is well‐known in adults, but data in young children are sparse.
Anne Louise de Barros Garioud   +4 more
wiley   +1 more source

Dialoger mellan kön och genus [Elektronisk resurs] [PDF]

open access: yes, 2005
Under det senaste decenniet har genetiken på basis av nya kunskaper om den mänskliga  arvsmassan producerat nytt vetande om biologiskt kön. Samtidigt har genusvetenskaplig forskning givit en fördjupad förståelse av den kulturella och sociala ...
Blomqvist, Martha,
core  

A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 460-473, March 2025.
Abstract In oncology drug development, measuring drug concentrations at the tumor site and at the targeted receptor remains an ongoing challenge. Positron emission tomography (PET)‐imaging is a promising noninvasive method to quantify intratumor exposure of a radiolabeled drug (biodistribution data) and target saturation by treatment doses in vivo ...
Robin Michelet   +8 more
wiley   +1 more source

Kön eller genus? [PDF]

open access: yes, 1999
Kön/genus är centrala begrepp inom det forskningsfält som kan sammanfattas under beteckningar som genusforskning, könsforskning eller könsteoretisk forskning. De grundläggande begreppen har därmed fått ge namn åt forskningsfältet.
Gothlin, Eva
core  

Hur görs kön? : En kritisk diskursanalys av remissvar i lagstiftningsprocessen om juridiskt kön [PDF]

open access: yes
Syftet med denna studie är att undersöka hur kön görs diskursivt i intresseorganisationers remissvar på politiska förslag om förändrade möjligheter att ändra juridiskt kön under perioden år 2018-2022. En kritisk diskursanalys genomförs enligt Faircloughs
Nygren, Frida
core   +2 more sources

Betulinic Acid Enema Alleviates Colitis by Targeting Vitamin D Receptor to Protect the Intestinal Mucosal Barrier and Modulate Mucosa‐Associated Microbiota

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with limited effectiveness and safety of current drug therapies. Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid present in traditional Chinese medicines used clinically as retention enemas for UC, but its direct effects and mechanisms remain unclear ...
Lina Dong   +7 more
wiley   +1 more source

Dette nummers samlede anmeldelser

open access: yesKvinder, Køn & Forskning, 2012
I dette nummer er følgnde bøger blevet anmeldt: Iben Jensen: Jobsamtaler med etniske minoriteter. Roskilde Universitetsforlag, 2011. Harriet Bjerrum Nielsen: Skoletid. Piger og drenge fra 1. til 9. klasse. Akademisk Forlag, 2011. Ane H.
Bettina W. Renninson   +3 more
doaj   +1 more source

Targeting protein–protein interactions with reversible covalent modalities: Non‐cysteine chemistries

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Protein–protein interactions (PPIs) are central to diverse cellular functions, and represent a rapidly expanding class of therapeutic targets. Advancements in covalent drug design have enabled small‐molecule drugs to overcome challenges associated with engaging these targets, such as limited durations of action and difficult‐to‐drug (expansive,
Ruchira Basu, Steven Fletcher
wiley   +1 more source

Ondanks ... en nogtans ’n Geleentheidswoord

open access: yesIn die Skriflig, 1998
By hierdie afskeidsfunksie wil ek, wat myself betref, die volgende stel: Ek is maar alte bewus van my sondes en gebreke. Dit is eerder ondanks myself dat die Here my nogtans in sy diens kon gebruik as op grond van iets wat ek sou wees.
J. A. van Rooy
doaj   +1 more source

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux   +26 more
wiley   +1 more source

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