Results 131 to 140 of about 73,773 (231)
Chlorogenic acid (CGA) inhibits Helicobacter pylori urease (HPU) through a mixed‐type mechanism. The CGA–HPU interaction is thermodynamically spontaneous and enthalpy‐driven (ΔG < 0, ΔH < 0), proceeding via a static quenching mode. Molecular dynamics simulations and structural studies reveal that CGA binds near the HPU active site and mobile flap ...
Luzhe Wu +6 more
wiley +1 more source
Temperature Dependent Motions of N‐Terminal Loop in PD‐1 Determine the Affinity Towards Nivolumab
ABSTRACT Programmed Cell Death—1 receptors on the surface of monocytes and T and B cells modulate various immune responses and are key immunotherapy targets. Immunotherapeutic monoclonal antibodies, including Nivolumab, block the activity of this receptor and are a mainstay of cancer therapy.
Mohammad Karbalaeimahdi +2 more
wiley +1 more source
Abstract The planning, design and management of urban green and blue spaces necessitate trade‐offs between these spaces' many benefits and their drawbacks, but knowledge of perceived problems and unpleasant experiences in urban green and blue spaces remains limited.
Alyssa L. Solvie +5 more
wiley +1 more source
Kampen om køn i idrættens verden
Hvis vi trækker det ned på jorden og i øjenhøjde med de frivillige idrætsforeninger, så kan vi ikke desto mindre gøre lidt, som kan vise sig at gøre en forskel.
Andersen, Tem Frank; id_orcid
core
Diverse Saturniidae moth communities are found in naturally recovering tropical forests in Ecuador. Community composition showed a gradual turnover with strongest differences between old‐growth forest and active agriculture, but only weak differences in taxonomic, phylogenetic and functional diversity. While our results suggest that Saturniidae are not
Sebastian Seibold +15 more
wiley +1 more source
ABSTRACT Background and Aim In Japan, gastric cancer (GC) and esophageal squamous cell carcinoma (ESCC) account for nearly all fatal upper gastrointestinal malignancies. A unified model that simultaneously predicts the incidence of these two cancers could help optimize endoscopic screening and postindex surveillance strategies.
Kenta Watanabe +26 more
wiley +1 more source
Drengeelever og pigeelever:- Hvordan skabes køn i skolen?
Ofte bliver køn og kønsforskelle diskuteret på en måde, der trækker på den gamle diskussion af, om arv eller miljø er (mest) determinerende for menneskers udvikling, og for de store forskelle, som kan konstateres mellem mennesker indenfor snart sagt alle
Krøjer, Jo
core
Using kanamycin A as a model target, we developed click‐capture SELEX to identify nucleobase‐modified aptamers capable of binding small molecules in solution. This approach enables flexible incorporation of nucleobase modifications via CuAAC, allowing the chemical properties of the aptamer to be tailored to the target molecule.
Philipp Menke +5 more
wiley +1 more source

