Results 161 to 170 of about 4,726,498 (283)

Educational robotics as a pedagogical resource for K-12 students with learning difficulties. [PDF]

open access: yesSci Rep
da Silva MDGT   +4 more
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Cost-effectiveness analysis of a text message system for COVID-19 testing for K-12 school communities. [PDF]

open access: yesJ Pediatric Infect Dis Soc
Dougherty M   +15 more
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Parental Involvement, Academic Self-Efficacy, and Depression on Academic Performance Among Chinese Students During COVID-19 Pandemic

open access: yesPsychology Research and Behavior Management
Lili Kang,1 Changle Li,1 Duohui Chen,2 Xinxin Bao3 1School of Health Management, Fujian Medical University, Fuzhou, People’s Republic of China; 2College of Public Health Sciences, Chulalongkorn University, Bangkok, Thailand; 3School of Foreign Language ...
Kang L, Li C, Chen D, Bao X
doaj  

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Safety of 6'-sialyllactose (6'-SL) sodium salt produced with a derivative strain (<i>Escherichia coli</i> K-12 MG1655 INB-6SL_02) of <i>E. coli</i> K-12 MG1655 (ATCC 700926) as a novel food pursuant to Regulation (EU) 2015/2283. [PDF]

open access: yesEFSA J
EFSA Panel on Nutrition   +23 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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