Results 241 to 250 of about 1,918 (281)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Latent Profiles of Deceased Organ Donation Registrants and Nonregistrants in the United States. [PDF]

J Transplant
Kirshenbaum AP, Parent B, Goodgame Huffman L, Kelsey V, Sofis MJ.   +4 more
europepmc   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Barriers and facilitators to implementing the birth preparedness and complication readiness strategy: midwives' perceptions. [PDF]

BMC Pregnancy Childbirth
Esan DT, Onilude KA, Ramos CG.
europepmc   +1 more source

The impact of cognitive schema on learning transfer ability and stability of classical Chinese poetry. [PDF]

PLoS One
Liu D, He P, Yan H.
europepmc   +1 more source

A study on the spatial dislocation relationship and influencing factors between the ICH and traditional villages in the Xiangjiang River Basin. [PDF]

Sci Rep
He C, Chen L, Liang Y.
europepmc   +1 more source

Maladaptive daydreaming should be included as a dissociative disorder in psychiatric manuals: position paper. [PDF]

Br J Psychiatry
Soffer-Dudek N, Somer E, Spiegel D, Chefetz R, O'Neil J, Dorahy MJ, Cardeña E, Mamah D, Schimmenti A, Musetti A, Boon S, van Dijke A, Ross C, Nijenhuis E, Krause-Utz A, Dell P, Gold SN, Pietkiewicz I, Silberg J, Steele K, Moskowitz A, Draijer N, Thomson P, Barach P, Kinsler P, Maves P, Şar V, Krüger C, Middleton W.   +28 more
europepmc   +1 more source

Break on Through: Betty Eisner's Problematic Use of Psychedelics, Groups, and Control for Integrative Experiences. [PDF]

J Hist Behav Sci
Davidson T, Plesa P.
europepmc   +1 more source

Trait psychoticism is associated with greater intersubject neural dissimilarity during naturalistic social movie viewing. [PDF]

Sci Rep
Kim MK, Jeong DW, Yoo DY, Kwak S.
europepmc   +1 more source