Results 151 to 160 of about 16,341,714 (282)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Discover Applied SciencesSurface dynamics are pivotal in shaping the Earth’s topography, which is convoluted with various geo-hazards such as mass movements and soil erosion processes.
Harish Khali +2 more
doaj +1 more source
Improved localization accuracy in stochastic super-resolution fluorescence microscopy by K-factor image deshadowing. [PDF]
Biomed Opt Express, 2013 Ilovitsh T +6 more
europepmc +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2002 25 pages, uses special included style file, 14 eps figures, submitted to Heavy Ion ...
openaire +2 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Ordered Factorizations with $k$ Factors
, 2016 We give an overview of combinatoric properties of the number of ordered $k$-factorizations $f_k(n,l)$ of an integer, where every factor is greater or equal to $l$. We show that for a large number $k$ of factors, the value of the cumulative sum $F_k(x,l)=\sum\nolimits_{n\leq x} f_k(n,l)$ is a polynomial in $\lfloor \log_l x \rfloor$ and give explicit ...
openaire +2 more sources
The Number of Connected Components in Graphs and Its Applications
, 2007 For any given graph and an integer k, the number of connected components with k vertices in the graph is investigated. For the vertex set of size n and the maximum degree 1, the number is bounded above by (e1) k (101)k . The factor 1 k is essential,
Ryuhei Uehara, K The Factor
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