Results 221 to 230 of about 1,835,018 (264)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

k -means: A revisit

open access: yesNeurocomputing, 2018
Abstract Due to its simplicity and versatility, k-means remains popular since it was proposed three decades ago. The performance of k-means has been enhanced from different perspectives over the years. Unfortunately, a good trade-off between quality and efficiency is hardly reached. In this paper, a novel k-means variant is presented.
Wan-Lei Zhao, Chong Wah Ngo
exaly   +4 more sources

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