Results 161 to 170 of about 15,852,135 (305)
Klustering Dengan K-Means Berbasis LVQ Dan K-Means Berbasis OWA
Jurnal Teknologi Informasi dan Ilmu Komputer, 2015 Dian Eka Ratnawati, Indriati .
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
A study on learning-augmented k-means clustering
reservedClustering is a practical approach for extracting meaningful information from unstructured data. With the exponential growth of data, it is essential to develop efficient methods for computing clusters.
PEPAJ, MARIA TERESA
core
Intrusion detection system using hybird gsa-k-means [PDF]
, 2013 Security is an important aspect in our daily life. Intrusion Detection Systems (IDS) are developed to be the defense against security threats. Current signature based IDS like firewalls and antiviruses, which rely on labeled training data, generally ...
Aslahi Shahri, Bibi Masoomeh
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
, 2023 The k-means clustering algorithm (k-means for short) provides a method offinding structure in input examples. It is also called the Lloyd–Forgy algorithm as it was independently introduced by both Stuart Lloyd and Edward Forgy. k-means, like other algorithms you will study in this part of the book, is an unsupervised learning algorithm and, as such ...
openaire +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source