Results 101 to 110 of about 940,524 (345)
Degeneracy on K-means clustering
Electronic Notes in Discrete Mathematics, 2012 Abstract The local search algorithm for K -means clustering could be degenerated. In other words, it could finish at a solution with less clusters than desired. These degenerate solutions impact the algorithm's quality and speed. In this paper I show that the local search algorithm for K-means clustering degenerates with some counter examples.
openaire +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Self-adaptive GA, quantitative semantic similarity measures and ontology-based text clustering [PDF]
, 2008 As the common clustering algorithms use vector space model (VSM) to represent document, the conceptual relationships between related terms which do not co-occur literally are ignored.
Wei Yu +7 more
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Implementasi KD-Tree K-Means Clustering untuk Klasterisasi Dokumen
Jurnal Teknik ITS, 2013 Klasterisasi dokumen adalah suatu proses pengelompokan dokumen secara otomatis dan unsupervised. Klasterisasi dokumen merupakan permasalahan yang sering ditemui dalam berbagai bidang seperti text mining dan sistem temu kembali informasi.
Eric Budiman Gosno +2 more
doaj
Deep soft K-means clustering with self-training for single-cell RNA sequence data
NAR Genomics and Bioinformatics, 2020 Single-cell RNA sequencing (scRNA-seq) allows researchers to study cell heterogeneity at the cellular level. A crucial step in analyzing scRNA-seq data is to cluster cells into subpopulations to facilitate subsequent downstream analysis.
Liang Chen +3 more
semanticscholar +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Centroid Update Approach to K-Means Clustering
Advances in Electrical and Computer Engineering, 2017 The volume and complexity of the data that is generated every day increased in the last years in an exponential manner. For processing the generated data in a quicker way the hardware capabilities evolved and new versions of algorithms were created ...
BORLEA, I.-D. +3 more
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source