Results 131 to 140 of about 940,524 (345)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Stock Data Clustering of Food and Beverage Company

open access: yesIJCCS (Indonesian Journal of Computing and Cybernetics Systems), 2007
Cluster analysis can be defined as identifying groups of similar objects to discover distribution of patterns and interesting correlations in large data sets.
Shofwatul Uyun, Subanar Subanar
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Fuzzy clustering of time series gene expression data with cubic-spline

open access: yes, 2013
Data clustering techniques have been applied to ex- tract information from gene expression data for two decades. A large volume of novel clustering algorithms have been developed and achieved great success.
Ali, Akhtar, Wang, Yu, Angelova, Maia
core   +1 more source

MODIFIKASI K-MEANS BERBASIS ORDERED WEIGHTED AVERAGING (OWA) UNTUK KASUS KLASTERING

open access: yesAgrointek, 2016
K-means clustering method based on Ordered Weighted Averaging (OWA) was developed by Cheng et al (2009) to resolve problem in classification using integrating k-means clustering and OWA.
Millatul Ulya Millatul Ulya
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Unsupervised clustering approach for network anomaly detection

open access: yes, 2012
This paper describes the advantages of using the anomaly detection approach over the misuse detection technique in detecting unknown network intrusions or attacks.
Syarif, Iwan   +2 more
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Implementation of K-means Clustering Algorithm using Java

open access: yes, 2011
Emergence of modern techniques for scientific data collection has resulted in large scale accumulation of data pertaining to diverse fields. Conventional database querying methods are inadequate to extract useful information from huge data analysis ...
Prof. S.China Venkateswarlu   +2 more
core  

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