Results 91 to 100 of about 57,228 (156)

Rapid screening and detection of inter-type viral recombinants using phylo-k-mers. [PDF]

open access: yesBioinformatics, 2021
Scholz GE   +4 more
europepmc   +1 more source

At‐RS31 orchestrates hierarchical cross‐regulation of splicing factors and integrates alternative splicing with TOR‐ABA pathways

open access: yesNew Phytologist, EarlyView.
Summary Alternative splicing is essential for plants, enabling a single gene to produce multiple transcript variants to boost functional diversity and fine‐tune responses to environmental and developmental cues. Arabidopsis thaliana At‐RS31, a plant‐specific splicing factor in the Serine/Arginine‐rich (SR) protein family, responds to light and the ...
Tino Köster   +18 more
wiley   +1 more source

Point‐of‐Care Testing by Multiplex‐PCR in Different Compartments in Suspected Lower Respiratory Tract Infection After Lung Transplantation—Results of a Prospective Study

open access: yesTransplant Infectious Disease, EarlyView.
Use of POCtmPCR with noninvasive samples (NPS and sputum) in LTx recipients with viral LRTI are a viable alternative to invasive BAL sampling, ABSTRACT Background Respiratory tract infections (RTIs) are a leading cause of morbidity and mortality following lung transplantation (LTx).
Susanne Simon   +4 more
wiley   +1 more source

Loc4Lnc: Accurate prediction of long noncoding RNA subcellular localization via enhanced RNA sequence representation

open access: yesQuantitative Biology, Volume 13, Issue 3, September 2025.
Abstract Long noncoding RNAs (lncRNAs) are crucial in gene regulation, chromatin architecture, and cellular differentiation, playing significant roles in various diseases and serving as potential biomarkers and therapeutic targets. Understanding their precise subcellular localization is essential for elucidating their functions in biological pathways ...
Yujia Cheng, Xiaoyong Pan, Yang Yang
wiley   +1 more source

AFLAP: assembly-free linkage analysis pipeline using k-mers from genome sequencing data. [PDF]

open access: yesGenome Biol, 2021
Fletcher K   +5 more
europepmc   +1 more source

How error correction affects polymerase chain reaction deduplication: A survey based on unique molecular identifier datasets of short reads

open access: yesQuantitative Biology, Volume 13, Issue 3, September 2025.
Abstract Next‐generation sequencing data are widely utilised for various downstream applications in bioinformatics and numerous techniques have been developed for PCR‐deduplication and error‐correction to eliminate bias and errors introduced during the sequencing.
Pengyao Ping   +4 more
wiley   +1 more source

Optimisation of Heated Electrospray Ionisation Parameters to Minimise In‐Source Generated Impurities in the Analysis of Oligonucleotide Therapeutics

open access: yesRapid Communications in Mass Spectrometry, Volume 39, Issue 13, 15 July 2025.
ABSTRACT Rationale Oligonucleotides have emerged as an important new class of therapeutic. Due to their structural complexity, this presents significant challenges for the development of analytical methods to characterise and determine their impurity profile.
Mollie A. Glenister   +4 more
wiley   +1 more source

Genomes of two Extinct‐in‐the‐Wild reptiles from Christmas Island reveal distinct evolutionary histories and conservation insights

open access: yesMolecular Ecology Resources, Volume 25, Issue 5, July 2025.
Abstract Genomics can play important roles in biodiversity conservation, especially for Extinct‐in‐the‐Wild species where genetic factors greatly influence risk of total extinction and probability of successful reintroductions. The Christmas Island blue‐tailed skink (Cryptoblepharus egeriae) and Lister's gecko (Lepidodactylus listeri) are two endemic ...
Tristram O. Dodge   +7 more
wiley   +1 more source

The promise and challenges of characterizing genome‐wide structural variants: A case study in a critically endangered parrot

open access: yesMolecular Ecology Resources, Volume 25, Issue 5, July 2025.
Abstract There is growing interest in the role of structural variants (SVs) as drivers of local adaptation and speciation. From a biodiversity genomics perspective, the characterization of genome‐wide SVs provides an exciting opportunity to complement single nucleotide polymorphisms (SNPs). However, little is known about the impacts of SV discovery and
Jana R. Wold   +4 more
wiley   +1 more source

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