Results 101 to 110 of about 57,228 (156)

COVID‐19‐Associated Cytotoxic Lesions of the Corpus Callosum in Chinese Patients: A Retrospective Study

Brain and Behavior, Volume 15, Issue 6, June 2025.
We report the clinical characteristics, radiological features, and changes in inflammatory markers throughout the entire course of illness in eight patients with COVID‐19‐associated CLOCCs. The neurological symptoms or signs in these patients included altered consciousness, headache, cognitive impairment, ataxia, dysarthria, pyramidal signs, and visual
Chenyi Wan, Menghua Li, Yanyan Yu, Si Luo, Daojun Hong, Meihong Zhou, Yu Zhu   +6 more
wiley   +1 more source

Peptide–Oligonucleotide Conjugates: Catalytic Preparation in Aqueous Solution or On‐Column

Current Protocols, Volume 5, Issue 6, June 2025.
Abstract Peptide–oligonucleotide conjugates (POCs) are synthesized through a novel catalytic and sustainable approach. The amide coupling between peptide and oligonucleotide is facilitated by 1,4‐diazabicyclo[2.2.2]octane (DABCO) as catalyst and 2‐chloro‐4,6‐dimethoxy‐1,3,5‐triazine (CDMT) as a stoichiometric activating agent.
Marion Gras, Michael Smietana, Pauline Adler   +2 more
wiley   +1 more source

A novel genotyping system based on site polymorphism on spike gene reveals the evolutionary pathway of porcine epidemic diarrhea virus

iMetaOmics, Volume 2, Issue 2, June 2025.
This study focuses on porcine epidemic diarrhea virus (PEDV), a highly virulent and rapidly evolving coronavirus threatening global swine production. We established a novel genotype system of PEDV targeting site‐specific polymorphisms in the spike (S) protein.
Mingkai Lei, Huimin Li, Xiaoyu Chen, Xiaozhen Li, Xuexiang Yu, Shengnan Ruan, Hao Wu, Ahmed H. Ghonaim, Ziyang Yan, Wentao Li, Qigai He   +10 more
wiley   +1 more source

Identification of potential SARS‐CoV‐2 genomic regions representing hallmarks for adaptation to different hosts

iMetaOmics, Volume 2, Issue 2, June 2025.
The k‐mer‐based pipeline, namely the Pathogen Origin Recognition Tool using Enriched K‐mers (PORT‐EK) identifies genomic regions enriched in the respective hosts after the comparison of multi‐genomes of isolates between different host species. The enriched k‐mer counts, which may serve as a potential marker, enable the classification and prediction of ...
Janusz Wiśniewski, Heng‐Chang Chen
wiley   +1 more source

Genetic and Inflammatory Signatures Associated With Worse Prognosis in Hospitalized Patients With Severe SARS‐CoV‐2 Infection With and Without Diabetes

Journal of Medical Virology, Volume 97, Issue 6, June 2025.
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SAR‐CoV‐2) presents with a diverse symptomology, ranging from asymptomatic to severe disease, but the mechanism of risk factors such as diabetes remains unelucidated. The current retrospective cohort study of 182 patients, with and without COVID‐19 and diabetes, analyzed leftover blood specimens
Marshall Yuan, Andrew Wassef, Davit Sargsyan, Vahe Nersisyan, Javier Cabrera, Ronald G. Nahass, Wael Hassan, Ah‐Ng Kong, Luigi Brunetti   +8 more
wiley   +1 more source

Reference-free Association Mapping from Sequencing Reads Using k-mers. [PDF]

Bio Protoc, 2020
Mehrab Z, Mobin J, Tahmid IA, Pachter L, Rahman A.   +4 more
europepmc   +1 more source

The Statistics of <i>k</i>-mers from a Sequence Undergoing a Simple Mutation Process Without Spurious Matches. [PDF]

J Comput Biol, 2022
Blanca A, Harris RS, Koslicki D, Medvedev P.   +3 more
europepmc   +1 more source

Long‐Term Sequelae of COVID‐19: A Systematic Review and Meta‐Analysis of Symptoms 3 Years Post‐SARS‐CoV‐2 Infection

Journal of Medical Virology, Volume 97, Issue 6, June 2025.
ABSTRACT The symptoms of long COVID are well‐documented. However, the long‐term effects beyond 2 years remain poorly understood due to a lack of data. This systematic review and meta‐analysis examined the prevalence of persistent symptoms in COVID‐19 survivors 3 years following initial SARS‐CoV‐2 infection.
Masoud Rahmati, Raphael Udeh, Jiseung Kang, Xenia Dolja‐Gore, Mark McEvoy, Abdolreza Kazemi, Pinar Soysal, Lee Smith, Tony Kenna, Guillaume Fond, Bastien Boussat, Duy Cao Nguyen, Huyen Do, Bach X. Tran, Nicola Veronese, Dong Keon Yon, Laurent Boyer   +16 more
wiley   +1 more source

Bacterial Outer Membrane Vesicles: From Physics to Clinical

MedComm – Biomaterials and Applications, Volume 4, Issue 2, June 2025.
A review of an introduction to the mechanisms of formation of OMVs, their action on bacteria and relationship to disease, vaccines, biomonitoring, drug delivery and regenerative medicine in the clinic. ABSTRACT Bacterial outer membrane vesicles (OMVs) are nanoscale vesicular structures naturally produced by Gram‐negative bacteria during growth.
Jun Zhou, Shuang Zou, Derong Dai, Liqing He, Xingyu Mou, Ninglin Zhao, Hong Li, Rui Bao   +7 more
wiley   +1 more source