Results 121 to 130 of about 57,228 (156)

Identification, validation, and characterization of approved and investigational drugs interfering with the SARS‐CoV‐2 endoribonuclease Nsp15

Protein Science, Volume 34, Issue 6, June 2025.
Abstract Since the emergence of SARS‐CoV‐2 at the end of 2019, the virus has caused significant global health and economic disruptions. Despite the rapid development of antiviral vaccines and some approved treatments such as remdesivir and paxlovid, effective antiviral pharmacological treatments for COVID‐19 patients remain limited. This study explores
Spyros D. Chatziefthymiou, Maria Kuzikov, Sara Afandi, Greta Kovacs, Sukrit Srivastava, Andrea Zaliani, Andrey Gruzinov, Guillaume Pompidor, Michele Lunelli, Golam Rizvee Ahmed, Jörg Labahn, Johanna Hakanpää, Björn Windshügel, Michael Kolbe   +13 more
wiley   +1 more source

Measuring Genome Sizes Using Read-Depth, k-mers, and Flow Cytometry: Methodological Comparisons in Beetles (Coleoptera). [PDF]

G3 (Bethesda), 2020
Pflug JM, Holmes VR, Burrus C, Johnston JS, Maddison DR.   +4 more
europepmc   +1 more source

Data structures based on k-mers for querying large collections of sequencing data sets. [PDF]

Genome Res, 2021
Marchet C, Boucher C, Puglisi SJ, Medvedev P, Salson M, Chikhi R.   +5 more
europepmc   +1 more source

Pandemic Prevention Paradigms: Understanding Global Health Governance

Public Health Challenges, Volume 4, Issue 2, June 2025.
One Health is an emerging area of integrative studies and interventions aimed at preventing zoonotic diseases by addressing human, animal, and environmental interactions. A fundamental aspect of the concept is understanding how these interactions influence health outcomes among humans, animals, and ecosystems. Developed initially to respond to the need
Soheil Sadr, Cinzia Santucciu, Valentina Chisu, Narges Lotfalizadeh, Shakiba Nazemian, Negin Esfandiari, Ashkan Hajjafari, Helia Sepahvand, Abbas Rahdar, Sadanand Pandey, Hassan Borji   +10 more
wiley   +1 more source

Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single‐cell RNA sequencing analyses

Quantitative Biology, Volume 13, Issue 2, June 2025.
Abstract The transcriptome, the complete set of RNA molecules within a cell, plays a critical role in regulating physiological processes. The advent of RNA sequencing (RNA‐seq) facilitated by Next Generation Sequencing (NGS) technologies, has revolutionized transcriptome research, providing unique insights into gene expression dynamics.
Jorge A. Tzec‐Interián, Daianna González‐Padilla, Elsa B. Góngora‐Castillo   +2 more
wiley   +1 more source

KmerGO: A Tool to Identify Group-Specific Sequences With k-mers. [PDF]

Front Microbiol, 2020
Wang Y, Chen Q, Deng C, Zheng Y, Sun F.
europepmc   +1 more source

Resilience and Mindfulness as Factors of Posttraumatic Stress and Growth Among Chinese Healthcare Workers During the COVID‐19 Pandemic: Mediation via Adaptive Coping and Stigmatisation

Stress and Health, Volume 41, Issue 3, June 2025.
ABSTRACT Experiences during the COVID‐19 pandemic may be traumatic to healthcare workers (HCWs). This study investigated the associations of resilience and mindfulness with posttraumatic stress symptoms (PTSS) and posttraumatic growth (PTG), and the mediation role of adaptive coping and stigmatisation related to HCWs' role in these associations from ...
Rui She, Lijuan Li, Qian Yang, Jianyan Lin, Xiaoli Ye, Suliu Wu, Zhenggui Yang, Suzhen Guan, Jianxin Zhang, Joseph Lau   +9 more
wiley   +1 more source

The backpack quotient filter: A dynamic and space-efficient data structure for querying k-mers with abundance. [PDF]

iScience
Levallois V, Andreace F, Le Gal B, Dufresne Y, Peterlongo P.   +4 more
europepmc   +1 more source

Land Use Change and Infectious Disease Emergence

Reviews of Geophysics, Volume 63, Issue 2, June 2025.
Abstract Major infectious diseases threatening human health are transmitted to people from animals or by arthropod vectors such as insects. In recent decades, disease outbreaks have become more common, especially in tropical regions, including new and emerging infections that were previously undetected or unknown. Even though there is growing awareness
M. Cristina Rulli, Paolo D’Odorico, Nikolas Galli, Reju S. John, Renata L. Muylaert, Monia Santini, David T. S. Hayman   +6 more
wiley   +1 more source

Impacts of Breaching Planetary Boundaries on Human Health: Current and Future Threats

GeoHealth, Volume 9, Issue 6, June 2025.
Abstract This review examines the impact of breaching planetary boundaries on human health and potential future threats, emphasizing the need for effective mitigation and adaptation strategies. Through a rigorous literature review of 142 high‐quality articles, we explore the health implications of breaching planetary boundaries such as climate change ...
Ricky Anak Kemarau, Zaini Sakawi, Oliver Valentine Eboy, Wan Shafrina Wan Mohd Jaafar, Zulfaqar Sa'adi, Stanley Anak Suab   +5 more
wiley   +1 more source