Results 41 to 50 of about 9,272,252 (254)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

KONTROL DIRI REMAJA PENGGEMAR K-POP (K-POPERS) (Studi pada Penggemar K-pop di Yogyakarta) [PDF]

open access: yes, 2018
AbstrakPenelitian ini bertujuan untuk mendeskripsikan secara lebih mendalam tentang kontrol diri pada remaja penggemar k-pop (k-popers) di Yogyakarta. Penelitian ini menggunakan metode deskriptif kualitatif dengan empat subjek yang merupakan remaja yang ...
Etikasari, Yulia
core   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Fan activism, cybervigilantism, and Othering mechanisms in K-pop fandom

open access: yesTransformative Works and Cultures, 2012
Korean popular music (K-pop) fandom may serve as a case study to identify both cynical and utopian views of fans' participatory Net activism by addressing three key aspects: fan activism, cybervigilantism, and Othering mechanisms. Fancom (fan company) in
Sun Jung
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

K-pop Subculture International Impact [PDF]

open access: yes, 2017
The overall purpose of this study was to gain a more in depth understanding of the conditions in which k-pop spread internationally. We initially knew that k-pop was an extremely popular sensation in Asian countries, specifically because it originated in
Spatichia, David, Otolorin, Monsurat
core   +1 more source

The Politics of Being a K-Pop Fan: Korean Fandom and the “Cancel the Japan Tour” Protest

open access: yesInternational Journal of Communication, 2023
This article focuses on the online protest by Korean K-pop fans during the 2019 trade dispute between Korea and Japan. Several fandoms demanded that entertainment agencies cancel upcoming concerts in Japan as part of a nationwide boycott of Japanese ...
Jennifer M. Kang
doaj  

Home - About - Disclaimer - Privacy