Results 101 to 110 of about 2,629,717 (284)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Scientific ReportsThis article presents an innovative sampling strategy, ordered moving extremes lower k-record ranked set sampling, designed to enhance parameter estimation and prediction for the generalized exponential distribution. By incorporating k-record values with
Haidy A. Newer
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
High‐Detectivity GeSn Mid‐Infrared Photodetectors for Sensitive Infrared Spectroscopy
Advanced Photonics ResearchInfrared (IR) spectroscopy is a powerful, nondestructive analytical technique that requires cost‐effective and highly sensitive IR photodetectors (PDs).
Meng‐Hsien Chou +6 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
The hot summer 2003 in Germany. Some preliminary results of a statistical time series analysis
Meteorologische Zeitschrift, 2004 A statistical analysis of the summer (June, July, and August) surface air temperature, time series 1761–2003, representative of Germany, is presented.
Christian D. Schönwiese +2 more
doaj +1 more source
Spatial variability of climate and past atmospheric circulation patterns from central West Antarctic glaciochemistry [PDF]
, 1999 Atmospheric circulation patterns and the spatial variability of atmospheric chemistry and moisture transport in central West Antarctica are investigated using new 40 year long (1954–1994 A.D.) glaciochemical and accumulation rate records developed from ...
Mayewski, Paul A. +4 more
core +3 more sources
k-anonymous Microdata Release via Post Randomisation Method
, 2015 The problem of the release of anonymized microdata is an important topic in the fields of statistical disclosure control (SDC) and privacy preserving data publishing (PPDP), and yet it remains sufficiently unsolved.
Chida, Koji +3 more
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source