Results 21 to 30 of about 42,939 (197)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

A New Asteroseismic Kepler Benchmark Constrains the Onset of Weakened Magnetic Braking in Mature Sun-like Stars

The Astrophysical Journal
Stellar spin down is a critical yet poorly understood component of stellar evolution. In particular, results from the Kepler Mission imply that mature age, solar-type stars have inefficient magnetic braking, resulting in a stalled spin-down rate. However,
Vanshree Bhalotia, Daniel Huber, Jennifer L. van Saders, Travis S. Metcalfe, Keivan G. Stassun, Timothy R. White, Víctor Aguirre Børsen-Koch, Warrick H. Ball, Sarbani Basu, Aldo M. Serenelli, Erica Sawczynec, Joyce A. Guzik, Andrew W. Howard, Howard Isaacson   +13 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Revealing a Main-sequence Star that Consumed a Planet with JWST

The Astrophysical Journal
The subluminous red nova (SLRN) Zwicky Transient Facility (ZTF) SLRN-2020 is the most compelling direct detection of a planet being consumed by its host star, a scenario known as a planetary engulfment event. We present JWST spectroscopy of ZTF SLRN-2020
Ryan M. Lau, Jacob E. Jencson, Colette Salyk, Kishalay De, Ori D. Fox, Matthew J. Hankins, Mansi M. Kasliwal, Charles D. Keyes, Morgan Macleod, Michael E. Ressler, Sam Rose   +10 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

MG1-1995959: An Eclipsing Binary Star with a Pronounced O’Connell Effect

The Astrophysical Journal
MG1-1995959 is a short-period (∼0.586 day) eclipsing binary, exhibiting at times an extraordinarily large O’Connell effect (OE), for which this paper reports its discovery, time series photometry, and spectroscopic observation.
Eric R. Craine, Brian L. Craine, Christopher J. Corbally, Adam L. Kraus, Andy S. Kulessa, Roger B. Culver, Grady Boyce, Tim B. Hunter, W. Marwood, Mike Miller, Geoffrey C. Stone   +10 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Hot Stars in the GALEX Ultraviolet Sky Surveys (GUVcat_AISxSDSS_HS) and the Binary Fraction of Hot Evolved Stars

The Astrophysical Journal Supplement Series
We present a catalog of 71,364 pointlike UV sources with Sloan Digital Sky Survey (SDSS) photometry and GALEX far-UV (FUV)−near-UV (NUV) ≤0.1 mag.
Luciana Bianchi
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Binary Yellow Supergiants in the Magellanic Clouds. I. Photometric Candidate Identification

The Astrophysical Journal
Recent works have constrained the binary fraction of evolved populations of massive stars in local galaxies such as red supergiants and Wolf–Rayet stars, but the binary fraction of yellow supergiants (YSGs) in the Hertzsprung gap remains unconstrained ...
Anna J. G. O’Grady, Maria R. Drout, Kathryn F. Neugent, Bethany Ludwig, Ylva Götberg, B. M. Gaensler   +5 more
doaj   +1 more source