Results 61 to 70 of about 532,841 (292)

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Stellar activity on the lower main sequence in Praesepe

open access: yes, 2004
An αΩ dynamo is considered responsible for magnetic activity in late K/early M main sequence stars, which is expected to be enhanced in later types as the surface convection zone deepens. At about spectral type M3, where the star presumably becomes fully
S. Kafka, R. Honeycutt
semanticscholar   +1 more source

Suzaku Detection of an Intense X-Ray Flare from an A-Type Star, HD161084 [PDF]

open access: yes, 2007
We report on a serendipitous detection of an intense X-ray flare from the Tycho reference source on HD 161084 during a Suzaku observation of the galactic center region for 20 ks.
J. Miura   +6 more
semanticscholar   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

X-Ray, FUV, and UV Observations of alpha Centauri B: Determination of Long-term Magnetic Activity Cycle and Rotation Period

open access: yes, 2010
We have been carrying out a study of stellar magnetic activity, dynamos, atmospheric physics, and spectral irradiances from a sample of solar-type G0-5 V stars with different ages.
Acton   +47 more
core   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

4FGL J1318.2+6754: A Long Orbital-period Redback Candidate

open access: yesThe Astrophysical Journal Letters
By combining the Fermi catalog and the single-lined spectroscopic binaries of Gaia Data Release 3 (DR3), we report a new candidate redback millisecond pulsar binary, which is recommended as a target for radio telescopes to detect pulsed signals.
Jie Lin   +3 more
doaj   +1 more source

The K supergiant runaway star HD 137071 [PDF]

open access: yes, 2020
Very few examples are known of red supergiant runaways, all of them descending from the more massive O-type precursors, but none from the lower mass B-type precursors, although runaway statistics among B-type stars suggest that K-type runaways must be relatively numerous. We study HD 137071, a star that has been considered so far as a normal K-type red
arxiv   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Time-series spectroscopy of the pulsating eclipsing binary XX Cephei

open access: yes, 2016
Oscillating Algol-type eclipsing binaries (oEA) are very interesting objects that have three observational features of eclipse, pulsation, and mass transfer.
Hong, Kyeongsoo   +4 more
core   +1 more source

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