Results 111 to 120 of about 78,958 (126)

K201, a multi-channel blocker, inhibits clofilium-induced torsades de pointes and attenuates an increase in repolarization

European Journal of Pharmacology, 2007
Hisashi Hasumi, Noboru Kaneko
exaly  

Effects of K201 on repolarization and arrhythmogenesis in anesthetized chronic atrioventricular block dogs susceptible to dofetilide-induced torsade de pointes

European Journal of Pharmacology, 2011
Jet D M Beekman
exaly  

K201 improves aspects of the contractile performance of human failing myocardium via reduction in Ca2+ leak from the sarcoplasmic reticulum

Basic Research in Cardiology, 2009
Jan Schmitto, Tim Seidler, Stephan E Lehnart   +2 more
exaly  

K201 (JTV-519) alters the spatiotemporal properties of diastolic Ca2+ release and the associated diastolic contraction during β-adrenergic stimulation in rat ventricular cardiomyocytes

Basic Research in Cardiology, 2011
Christopher Loughrey, Godfrey Smith, R Matsuda   +2 more
exaly  

Protective Effect of K201 on Isoproterenol-Induced and Ischemic–Reperfusion-Induced Ventricular Arrhythmias in the Rat

Journal of Cardiovascular Pharmacology and Therapeutics, 2013
Naoyuki Otani, Setsu Nishino, Noboru Kaneko   +2 more
exaly  

A mechanism of ryanodine receptor modulation by FKBP12/12.6, protein kinase A, and K201

Cardiovascular Research, 2010
Tony Lai
exaly  

Effect of K201, a novel antiarrhythmic drug on calcium handling and arrhythmogenic activity of pulmonary vein cardiomyocytes

British Journal of Pharmacology, 2008

exaly  

JTV519 (K201) reduces sarcoplasmic reticulum Ca2+ leak and improves diastolic function in vitro in murine and human non‐failing myocardium

British Journal of Pharmacology, 2012
Markus Wallner, Simon Sedej, Frank R Heinzel   +2 more
exaly  

K201 (JTV519) suppresses spontaneous Ca2+ release and [3H]ryanodine binding to RyR2 irrespective of FKBP12.6 association

Biochemical Journal, 2007
S R Wayne Chen, Pete Jones
exaly  

K201 (JTV519) is a Ca2+-Dependent Blocker of SERCA and a Partial Agonist of Ryanodine Receptors in Striated Muscle

Molecular Pharmacology, 2016
Paula Diaz-Sylvester, Julio Copello
exaly