Results 111 to 120 of about 59,826 (127)

Inhibition of annexin V-dependent Ca2+ movement in large unilamellar vesicles by K201, a new 1,4-benzothiazepine derivative

Biochimica Et Biophysica Acta - Biomembranes, 1997
Examination was made of the effect of annexin V on Ca2+ movement into large unilamellar vesicles (LUV) using fura-2, a calcium-sensitive fluorescent dye.
Noboru Kaneko, Ryuko Matsuda, Ken Shimamoto   +2 more
exaly   +2 more sources

Cardiac ryanodine receptor in metabolic syndrome: is JTV519 (K201) future therapy?

Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 2012
U Deniz DincerDepartment of Pharmacology, Ufuk University School of Medicine. Mevlana Bulvari, Balgat, Ankara, TurkeyAbstract: Metabolic syndrome is characterized by a combination of obesity, hypertension, insulin resistance, dyslipidemia, and impaired ...
U Deniz Dinçer
exaly   +2 more sources

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K201 improves aspects of the contractile performance of human failing myocardium via reduction in Ca2+ leak from the sarcoplasmic reticulum

Basic Research in Cardiology, 2009
Karl Toischer, Reiner Korfer, Jan D Schmitto   +2 more
exaly  

K201, a multi-channel blocker, inhibits clofilium-induced torsades de pointes and attenuates an increase in repolarization

European Journal of Pharmacology, 2007
Ryuko Matsuda, Ken Shimamoto, Noboru Kaneko   +2 more
exaly  

K201 (JTV-519) alters the spatiotemporal properties of diastolic Ca2+ release and the associated diastolic contraction during β-adrenergic stimulation in rat ventricular cardiomyocytes

Basic Research in Cardiology, 2011
Hideyo Hasumi, Ryuko Matsuda, Christopher M Loughrey   +2 more
exaly  

Effects of K201 on repolarization and arrhythmogenesis in anesthetized chronic atrioventricular block dogs susceptible to dofetilide-induced torsade de pointes

European Journal of Pharmacology, 2011
Avram Oros, Jet D M Beekman, Marc A Voß   +2 more
exaly  

K201 (JTV519) is a Ca2+-Dependent Blocker of SERCA and a Partial Agonist of Ryanodine Receptors in Striated Muscle

Molecular Pharmacology, 2016
Paula L Diaz-Sylvester, Julio A Copello
exaly  

New 1,4-benzothiazepine derivative, K201, demonstrates cardioprotective effects against sudden cardiac cell death and intracellular calcium blocking action

Drug Development Research, 1994
Noboru Kaneko
exaly  

A mechanism of ryanodine receptor modulation by FKBP12/12.6, protein kinase A, and K201

Cardiovascular Research, 2010
F Anthony Lai, Lai F Anthony
exaly  

K201 (JTV519) suppresses spontaneous Ca2+ release and [3H]ryanodine binding to RyR2 irrespective of FKBP12.6 association

Biochemical Journal, 2007
Peter P Jones, Ruiwu Wang, Jeff Bolstad   +2 more
exaly