King K201 confocal right cornea [PDF]
Right corneal confocal micrographs obtained post mortem from king penguin ...
Charles McGhee (1187247) +5 more
core +1 more source
King K201 confocal left cornea [PDF]
Left corneal confocal micrographs obtained post mortem from king penguin K201
Charles McGhee (1187247) +5 more
core +1 more source
Petrology and geochemistry of basalt at DSDP Hole 66-487 [PDF]
Major oxide and trace element determinations of the composition basalts from the bottom of Hole 487, together with microprobe analyses of their minerals (olivine, magnesiochromite, salite, and plagioclase), prove that they are depleted oceanic ...
Maury, R C +7 more
core +1 more source
A mechanism of ryanodine receptor modulation by FKBP12/12.6, protein kinase A, and K201 [PDF]
Aims Our objective was to explore the functional interdependence of protein kinase A (PKA) phosphorylation with binding of modulatory FK506 binding proteins (FKBP12/12.6) to the ryanodine receptor (RyR).
Blayney, Lynda Mary +3 more
core +1 more source
K201 improves aspects of the contractile performance of human failing myocardium via reduction in Ca2+ leak from the sarcoplasmic reticulum [PDF]
In heart failure, intracellular Ca<sup>2+</sup> leak from cardiac ryanodine receptors (RyR2s) leads to a loss of Ca<sup>2+</sup> from the sarcoplasmic reticulum (SR) potentially contributing to decreased function ...
Körfer, R. +35 more
core +1 more source
(Table 1) Geochemistry of Cocos Plate hemipelagic-pelagic sediments in DSDP Hole 66-487 [PDF]
The sedimentary sequence recovered from Hole 487 documents northeast seafloor spreading on the Cocos Plate. A basal 65-meter unit of upper Miocene-Pliocene brown clay was deposited on the subsiding east flank of the East Pacific Rise.
Leggett, Jeremy K +1 more
core +1 more source
K201 (JTV-519) alters the spatiotemporal properties of diastolic Ca2+ release and the associated diastolic contraction during β-adrenergic stimulation in rat ventricular cardiomyocytes [PDF]
K201 has previously been shown to reduce diastolic contractions in vivo during beta-adrenergic stimulation and elevated extracellular calcium concentration ([Ca<sup>2+</sup>]<sub>o</sub>).
Hasumi, H. +15 more
core +1 more source
心室細動とその抑制機序に関する実験的検討 : ベンゾチアゼピン誘導体K201とジルチアゼムの比較検討 [PDF]
Ca^負荷下イソプロテレノール誘発心室細動(Iso-Vf)および虚血再灌流誘発心室細動(Rep-Vf)に対するベンゾチアゼピン誘導体K201およびジルチアゼムの抑制効果を検討した. Wistar雄性ラットを用い,Ca^負荷(12mg/kg/min) 20分間後イソプロテレノール(0.6μg/kg/分)を20分間投与した.虚血再灌流実験では左冠動脈前下行枝を結紮5分後再灌流した.
大谷, 直由 +1 more
core +1 more source
A Novel Cardioprotective Drug, K201 (JTV519), Induces Prolongation of QT and QTc Intervals, but not Torsades de Pointes [PDF]
K201 (JTV-519; 4-[-3{1-(4-benzyl) piperidinyl} propionyl]-7-methoxy-2, 3, 4, 5-tetrahydro-1, 4-ben-zothiazepine), is a multi-channel blocker and a ryanodine receptor stabilizer that exhibits strong cardiopro-tective and antiarrhythmic effects.
Matsuda, Toshiya +4 more
core +1 more source
Acetylation of PhoP K201 regulates intracellular replication and inflammation response in macrophages. [PDF]
(A) The replication of bacteria in RAW264.7 cells. Net growth between 2 h and 24 h was calculated from the fold change in c.f.u. /ml recovered at these time points. Error bars represented SD from at least three independent experiments.
Shuting Liu (500724) +10 more
core +1 more source

