Results 11 to 20 of about 115 (69)

Targeting and Energy‐Depleting Biomimetic Nanoparticles for Enhancing Combined Chemo‐Sonodynamic Therapy Against Esophageal Cancer

Rare Metals, Volume 45, Issue 8, August 2026.
ABSTRACT Esophageal cancer is the seventh leading cause of cancer death, and the energy depletion in cancer cells can be achieved through synergistic therapy. The integration of sonodynamic therapy and chemotherapy offers a promising comprehensive treatment strategy for esophageal cancer.
Mengya Li, Ruimei Jin, Shengxi Zhou, Jingan Li, Kun Zhang   +4 more
wiley   +1 more source

Acoustically Assisted Heterojunction Hydrogel Promotes Angiogenesis and Tissue Regeneration by Modulating the Inflammatory Microenvironment

Rare Metals, Volume 45, Issue 8, August 2026.
ABSTRACT The healing of diabetic chronic wounds is hindered by multiple pathological barriers, including oxidative stress imbalance induced by hyperglycemia, persistent bacterial infection, and impaired neovascular function. This study developed an F127–HA–BiOCl@CeO2 (FHBC) hydrogel dressing with acoustic responsiveness, achieving tissue repair through
Ran Zhao, Yixuan Song, Wencan Zhang, Chen Liu, Xichao Wang, Xinyang Guo, Jiaming Zhang, Zihao Liu, Le Li   +8 more
wiley   +1 more source

Dual‐Bioactive Lignin‐Based Microcarrier Hydrogel Platform via Metal Salt Crosslinking for Synchronized Infection Eradication and Bone Regeneration

Rare Metals, Volume 45, Issue 8, August 2026.
ABSTRACT Infected bone defects represent a dual therapeutic challenge demanding concurrent infection inhibition and osteogenesis promotion. Systemic antibiotic administration is taken as a classical treatment protocol but often yields inadequate local antibiotic concentrations and delayed bone repair.
Xucai Wang, Yuxiang Fei, Zhenbo Yuan, Qiuyang Wang, Haojun Chen, Peng Wang, Weijun Wang, Wenbo Chen, Caoxing Huang   +8 more
wiley   +1 more source

Cross‐stage single‐cell and spatial metabolome analyses reveal periderm specialization and tanshinone biosynthesis in Salvia miltiorrhiza roots

New Phytologist, Volume 251, Issue 3, Page 1267-1282, August 2026.
Biosynthesis and accumulation of tanshinones in the periderm of Salvia miltiorrhiza during secondary root growth. Summary Perennial herbs develop long‐lived roots that undergo repeated cycles of secondary growth, during which the periderm functions as a protective barrier and a major site of specialized metabolite accumulation.
Licheng Liu, Lianchong Gao, Zhi‐Ying Wang, Yan Liu, Huifeng Ju, Huana Lin, Zheng Shi, Wen‐Juan Cai, Xue Li, Yan‐Bo Huang, Yu Kong, Jing‐Jing Xu, Hong‐Peng Chen, Xin Fang, Juan Guo, Yong‐Hong Hu, Ke Chen, Xiao‐Ya Chen, Jie Hao, Lei Yang   +19 more
wiley   +1 more source

A pH‐Responsive Biomimetic Nanoparticle Coated With Macrophage Membranes for Photothermal and Immunotherapy of Bladder Cancer

Rare Metals, Volume 45, Issue 7, July 2026.
ABSTRACT Tumor metastasis and recurrence are major reasons for the difficulty in curing cancer. Although some immunotherapy methods have been developed, they are still limited by immunosuppression, resulting in limited therapeutic efficacy against tumors.
Chen Ye, Wenli Jiang, Zhensheng Zhang, Huiqing Wang, Guanghua Chen   +4 more
wiley   +1 more source

Spatiotemporally Adaptive Bilayer Silk Fibroin–Polyvinyl Alcohol–Metformin Composite Coating on Biodegradable Zinc for Orthopedic Applications

Rare Metals, Volume 45, Issue 7, July 2026.
ABSTRACT Biodegradable zinc (Zn)‐based materials are considered promising candidates for orthopedic applications because of their favorable mechanical properties, controllable biodegradability, and good biosafety profiles. However, their clinical translation is limited by early‐stage corrosion‐induced cytotoxicity and inflammation, as well as ...
Jinlong Mao, Wentai Zhang, Jingtao Dai, Zhaozhao Zhang, Junyu Qian, Jinjing Liu, Wenjie Tao, Yuanhao Wang, Dorothea Alexander, Guojiang Wan   +9 more
wiley   +1 more source

Preparation of Highly Bioactive Nanolignin via Dopamine Mannich Modification and Its Synergistic Effects With Zn2+ in PVA Hydrogels

Rare Metals, Volume 45, Issue 7, July 2026.
ABSTRACT Lignin is a natural non‐toxic polyphenolic macromolecule, which shows inherent antioxidant and broad‐spectrum antibacterial activities. However, due to the low content and the high bond dissociation energy of phenolic hydroxyl groups (Ar‐O·H), its antioxidant and antibacterial activities are relatively weak, which limits its application as a ...
Meiling Han, Hui Hui, Yi Yang, Yan Wang, Danli Zhou, Yuebin Xi, Yu Jing, Pingxian Feng, Fan‐Gong Kong, Huan Wang, Weijun Yang   +10 more
wiley   +1 more source

Microwave‐Actuated CuS/CuCo2O4 Heterojunction Microneedles for Synergistic Eradication of Deep‐Seated Biofilms and Inflammatory Microenvironment Remodeling in Acne Treatment

Rare Metals, Volume 45, Issue 7, July 2026.
ABSTRACT Deep skin infections and dense biofilm barriers caused by Propionibacterium acnes (P. acnes) remain significant challenges in recurrent acne vulgaris, exacerbated by the poor stratum corneum penetration of conventional therapies and rising antibiotic resistance.
Bingran Qi, Chang Zheng, Shifeng Jin, Kezhu Li   +3 more
wiley   +1 more source

Targeting Inflammaging: A Metformin‐Releasing Titanium Implant Reprograms Senescent Macrophages to Orchestrate Angiogenesis and Osteogenesis

Rare Metals, Volume 45, Issue 7, July 2026.
ABSTRACT Bone defect repair in elderly patients is frequently compromised by reduced osteogenic capacity and delayed healing. Chronic inflammation‐driven inflammaging is a critical contributor to this impairment, characterized by dysfunctional autophagy in senescent macrophages (S‐MΦs), excessive reactive oxygen species (ROS) accumulation, and ...
Ruiyue Hang, Ruoyu Di, Yuyu Zhao, Jiahui Wang, Xiaohong Yao, Ruiqiang Hang, Yin Xiao   +6 more
wiley   +1 more source

An Organo‐Pt(II) Photosensitizer With Robust Photo‐Assisted Antibacterial and Wound Recovery Performances in Diabetic Mice Wound Model

Rare Metals, Volume 45, Issue 7, July 2026.
ABSTRACT The pathogenesis of diabetic foot ulcers is complex, often involving polymicrobial infection and persistent inflammatory responses, which lead to delayed or nonhealing wounds, posing a formidable clinical challenge. Existing photodynamic therapy reagents and traditional treatments generally address only a single pathological aspect, and the ...
Yu Zhang, Mengyao Han, Qianqian Cheng, Yin Jie, Qianqian Zheng, Ziwei Xu, Beixi Shi, Yueqi Zhao, Xiaofei Yang, Guangjie Zhong, Chenchen Chang, Xiaoxiao Yin, Xinai Zhong, Zhengru Fu, Shuying Bai, Hui Chong, Chengyin Wang   +16 more
wiley   +1 more source