Results 101 to 110 of about 1,608,475 (285)
, 2014 P a j a k a da l a h i u r a n r a k y a t k e pa d a ka s n e g a r a be r da s a r ka n und a n g und a ng Ke g i a t a n P r a kt e k Ke r j a N y a t a a d a l a ...
An d i k a P u r n a Ad i t ya
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
K R I S I S P O L I T I K D I S U R I A H E R A B A S H A R A L A S S A D
, 2014 R e v o l u s i T i m u r T e n g a h t e l a h m e n g i n s p i r a s i a n a k a n a k D e r a a y a n g m e n y e r u k a n s l o g a n m e n j a
Y E N N Y K U R N I A W A T I
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
, 2014 P e n d i d i k a n m e r u p a k a n k e b u t u h a n y a n g s a n g a t f u n d a m e n t a l b a g i s e t i a p i n d i v i d u b a i k s e c a r a f
N u r h a y a t i
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gradient estimates for a class of elliptic equations with logarithmic terms
Boundary Value ProblemsWe obtain the gradient estimates of the positive solutions to a nonlinear elliptic equation on an n-dimensional complete Riemannian manifold ( M , g ) $(M, g)$ Δ u + a u ( ln u ) p + b u ln u = 0 , $$ \Delta u +au(\ln{u})^{p}+bu\ln{u}=0, $$ where a ≠ 0 ...
Ze Gao, Qiming Guo
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
, 2014 P e m b u a n g a n l u m p u r l a p i n d o k e K a l i P o r o n g m e n y e b a b k a n p e r u b a h a n m o r f o l o g i s e c a r a t e r u s m e n
I w a n B u d i W i j a y a
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, 2014 Ta na man pa di mer upa k a n tana man budida y a uta ma mas y a ra ka t I ndone si a . Na mun, budida y a tan a man pa di mene mui du a ko ndisi c e ka man y a n g diak ibatka n oleh ...
S iti Nu r Wah yu T r is u si la Nin gr u m
core +1 more source