Results 141 to 150 of about 1,608,475 (285)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

"Ti???u thuy???t xu???t hi???n t???i nam k???"

, 1994
This article is a Vietnamese translation of "The Novel Appears in Cochinchina" which is also available in Humboldt Digital Scholar.M??i cho ?????n nh???ng n??m cu???i c???a th???p ni??n 1980 v?? ?????u th???p ni??n 1990 c??c nh?? v??n h???c s???
Schafer, John C., Th??? Uy??n
core  

Positive solutions of $\Delta u+K(x)u\sp p=0$ without decay conditions on $K(x)$ [PDF]

Proceedings of the American Mathematical Society, 1992
openaire   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

U P A Y A P EN I N G K A TA N A K TI V I TA S BELA J A R D A N H A SI L BELA J A R D EN G A N STR A TEG I CO N CEP T M AP P I N G D I SER TA I M ETO D E P EM BER I A N TU G A S A TA U R ESI TA SI P A D A SI SW A K ELA S V I I G SEM EST ER G EN A P TA H U N A J A R A N 2 0 1 2 / 2 0 1 3 SM P N 4 J EM BER

, 2014
F i s i ka a da l a h ba g i a n da r i s a i ns y a n g m e nj e l a s ka n be r ba g a i g e j a l a a l a m s e c a r a s i s t e m a t i s da n pe n y a j i a n
Je n n y O k a P u s p i t as ar i
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Polyfunctional Ligand of the Clinical Setting: Thermodynamic Studies of the Equilibria of Tranexamic Acid in Aqueous Solutions. [PDF]

ACS Omega
Bretti C, Cigala RM, De Stefano C, Crea F.   +3 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

E V A L U A S I P E L A K S A N A A N P E N D I S T R I B U S I A N P R O G R A M B E R A S M I S K I N ( R A S K I N ) T A H U N 2 0 1 1 D I D E S A G E N T E N G K U L O N K E C A M A T A N G E N T E N G K A B U P A T E N B A N Y U W A N G I

, 2014
P r o g r a m B e r a s U n t u k K e l u a r g a M i s k i n ( R a s k i n ) m e r u p a k a n s a l a h s a t u s t r a t e g i p e m e r i n t a h d a ...
R i n a B u d i a r t i
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