Results 251 to 260 of about 48,573 (291)
Some of the next articles are maybe not open access.
Related searches:
Related searches:
The Neuroscientist, 2013
Ionotropic glutamate receptors of the N-methyl-d-aspartate (NMDA)- and AMPA-type, as well as metabotropic glutamate receptors have been extensively invoked in plasticity. Until relatively recently, however, kainate-type receptors (KARs) had been the most elusive to study because of the lack of appropriate pharmacological tools to specifically address ...
Talvinder S, Sihra +2 more
openaire +3 more sources
Ionotropic glutamate receptors of the N-methyl-d-aspartate (NMDA)- and AMPA-type, as well as metabotropic glutamate receptors have been extensively invoked in plasticity. Until relatively recently, however, kainate-type receptors (KARs) had been the most elusive to study because of the lack of appropriate pharmacological tools to specifically address ...
Talvinder S, Sihra +2 more
openaire +3 more sources
Kainate receptors in the hippocampus
European Journal of Neuroscience, 2014AbstractKainate receptors (KARs) consist of a family of ionotropic glutamate receptors composed of the combinations of five subunits, GluK1–GluK5. Although KARs display close structural homology with AMPA receptors, they serve quite distinct functions.
Mario, Carta +3 more
openaire +3 more sources
Cell and Tissue Research, 2006
Kainate receptors form a family of ionotropic glutamate receptors that appear to play a special role in the regulation of the activity of synaptic networks. This review first describes briefly the molecular and pharmacological properties of native and recombinant kainate receptors.
Paulo, Pinheiro, Christophe, Mulle
openaire +2 more sources
Kainate receptors form a family of ionotropic glutamate receptors that appear to play a special role in the regulation of the activity of synaptic networks. This review first describes briefly the molecular and pharmacological properties of native and recombinant kainate receptors.
Paulo, Pinheiro, Christophe, Mulle
openaire +2 more sources
Current Opinion in Neurobiology, 2000
Kainate receptors are a family of ionotropic glutamate receptors with poorly understood functions. Recent evidence firmly establishes kainate receptors as postsynaptic mediators of synaptic transmission. A second, presynaptic, modulatory role of kainate receptors has also been suggested, although the mechanism(s) involved remain controversial.
M, Frerking, R A, Nicoll
openaire +2 more sources
Kainate receptors are a family of ionotropic glutamate receptors with poorly understood functions. Recent evidence firmly establishes kainate receptors as postsynaptic mediators of synaptic transmission. A second, presynaptic, modulatory role of kainate receptors has also been suggested, although the mechanism(s) involved remain controversial.
M, Frerking, R A, Nicoll
openaire +2 more sources
2010
Glutamate is the major fast excitatory amino acid transmitter in the CNS, and exerts its action through receptors that function as ion channels such as NMDA receptors (NMDARs), AMPA receptors (AMPARs), and kainate receptors (KARs), and also through signaling cascades via metabotropic receptors.
Erik B, Bloss, Richard G, Hunter
openaire +2 more sources
Glutamate is the major fast excitatory amino acid transmitter in the CNS, and exerts its action through receptors that function as ion channels such as NMDA receptors (NMDARs), AMPA receptors (AMPARs), and kainate receptors (KARs), and also through signaling cascades via metabotropic receptors.
Erik B, Bloss, Richard G, Hunter
openaire +2 more sources
Kainate induces various domain closures in AMPA and kainate receptors
Neurochemistry International, 2012Ionotropic glutamate receptors are key players in fast excitatory synaptic transmission within the central nervous system. These receptors have been divided into three subfamilies: the N-methyl-d-aspartic acid (NMDA), 2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) and kainate receptors.
Venskutonyte, Raminta +6 more
openaire +3 more sources
Current Pharmaceutical Design, 1996
AMPA and kainate receptors belong to a common family of ionotropic glutamate receptors. Molecular biology has revealed some of the molecular features that are responsible for selective ion permeability of the receptor comp.lex. The diversity of subunits and their combination into hetero-oligomeric recep or complexes have provided evidence that ...
Christopher F. Bigge +2 more
openaire +1 more source
AMPA and kainate receptors belong to a common family of ionotropic glutamate receptors. Molecular biology has revealed some of the molecular features that are responsible for selective ion permeability of the receptor comp.lex. The diversity of subunits and their combination into hetero-oligomeric recep or complexes have provided evidence that ...
Christopher F. Bigge +2 more
openaire +1 more source
Kainate receptors and synaptic plasticity
Nature, 2000Bortolotto et al.1 report that the kainate subtype of glutamate receptor is essential for the plasticity of certain types of synaptic transmission in the brain, which is of interest as these receptors were previously not thought to initiate plastic processes. In particular, a new antagonist (LY382884) was shown to act selectively against the GluR5 type
R A, Nicoll +3 more
openaire +2 more sources