Results 31 to 40 of about 11,360 (191)
INTRODUCTION: Human immunodeficiency virus (HIV) coinfection with Leishmania infantum or Leishmania donovani, the agents of visceral leishmaniasis (or kala-azar), has become a fatal public health problem in the tropics where kala-azar is endemic.
Iúri Paz Lima +5 more
doaj +3 more sources
ABSTRACT The present study assessed the leishmanicidal activity of 4‐nerolidylcatechol (4‐NC) (1) isolated from Piper peltatum leaves against promastigotes and amastigotes of Leishmania amazonensis, L. braziliensis, and L. infantum. The plant was fractionated, leading to the isolation and chemical identification of 4‐NC (1). Biochemical techniques were
Fabiana Brusco Lorenzetti +8 more
wiley +1 more source
Sex in Immune Cells and Parasitic Diseases — A Complex Relationship
ABSTRACT Epidemiological studies consistently show that many parasitic diseases affect males more frequently than females. These disparities are multifactorial, arising partly from gender‐specific behaviors that influence exposure risk and health‐seeking practices, especially in low‐ and middle‐income countries. Increasing evidence also highlights that
Barbara Honecker +2 more
wiley +1 more source
Mechanisms of Immune Evasion, Dissemination, and Persistence in Leishmania amazonensis Infection
ABSTRACT Leishmania amazonensis is one of the etiological agents of cutaneous leishmaniasis in its localised form. Moreover, this parasite can cause more severe disease conditions, such as diffuse and disseminated cutaneous leishmaniasis. The development of more severe clinical manifestations is associated with the parasite's ability to establish a ...
Arieli Bernardo Portugal +3 more
wiley +1 more source
Diagnostic Challenges in Visceral Leishmaniasis in a 17‐Month‐Old Female: A Case Report
ABSTRACT Visceral leishmaniasis is an uncommon infectious disease. In this report, we present a case of VL in a 17‐month‐old child who presented with a fever and splenomegaly. After the patient failed to respond to several courses of antibiotics, a bone marrow aspirate confirmed the definitive diagnosis of VL, which was successfully treated with ...
Ahmed Sheikh Sobeh +4 more
wiley +1 more source
Kala-azar in Maraveh Tapeh county, Golestan Provice, Iran: Seven case reports
Visceral leishmaniasis, also known as Kala-azar, is one of the main parasitic vector borne diseases, which transmitted by sand fly. The current study reported the seven positive cases of Kala-azar in Maravetapeh county in Golestan province, Iran from ...
M Qorbani +5 more
doaj
Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley +1 more source
Introduction: Leishmaniasis currently threatens 350 million men, women and children around the world. Visceral leishmaniasis (VL) is a fatal parasitic disease mostly prevalent in low land areas VL typically affects migrant agricultural workers.
Sisay Awoke +3 more
doaj +1 more source
ABSTRACT Cutaneous leishmaniasis (CL) remains a therapeutic challenge in endemic regions, with 600,000–1 million new cases annually facing limited treatment options. We present a case series evaluating an innovative topical combination therapy for acute‐phase CL in Shiraz, Iran.
Hoda Haghshenas +3 more
wiley +1 more source
Post-kala-azar dermal leishmaniasis (PKDL) drug efficacy study landscape: a systematic scoping review of clinical trials and observational studies to assess the feasibility of establishing an individual participant-level data (IPD) platform [PDF]
Sauman Singh-Phulgenda +16 more
openalex +1 more source

