Results 121 to 130 of about 726,321 (348)

Existentialism and My ‘Postwolf’ Dachshund: Authenticity in the Age of Genetic Engineering

open access: yesBioethics, EarlyView.
ABSTRACT Human genetic engineering has the potential to profoundly alter the traits of future generations, raising critical ethical questions about authenticity and identity. Essentialist perspectives reject genetic engineering, claiming it inherently compromises authenticity by deviating from a species‐typical genome.
Donrich Thaldar
wiley   +1 more source

Directs effects of granulocyte-macrophage colony stimulating factor (GM-CSF) on adaptive immunogenesis

open access: yesHuman Vaccines & Immunotherapeutics, 2019
Background: We studied direct effects of human granulocyte-macrophage colony stimulating factor (GM-CSF) on phenotypical characteristics and cytokine-production of non-activated and activated human monocytes/macrophages (Mc/Mphs) and T cells.
Victor Ivanovich Seledtsov   +5 more
doaj   +1 more source

Interrelation of chemerin and TNF-α with mtDNA copy number in adipose tissues and blood cells in obese patients with and without type 2 diabetes

open access: yesBMC Medical Genomics, 2019
Background Inflammatory response plays a key role in the development of insulin resistance (IR) in obesity. Oxidative stress triggers the replication of the mitochondrial genome and division of the organelle. The purpose of this study was to identify the
Daria Skuratovskaia   +4 more
doaj   +1 more source

Kant, Bolzano, and the Formality of Logic [PDF]

open access: yes, 2014
In §12 of his 1837 magnum opus, the Wissenschaftslehre, Bolzano remarks that “In the new logic textbooks one reads almost constantly that ‘in logic one must consider not the material of thought but the mere form of thought, for which reason logic ...
Stang, Nicholas
core  

Thoughtful Accompaniment in Life's Final Stages: Philosophical Practice as a Complement to Ethics Consultation

open access: yesBioethics, EarlyView.
ABSTRACT This paper argues that philosophical practice can complement existing medical ethics structures by offering a publicly accessible space for discourse and negotiation of basic concepts that are relevant to ethical decision making. The potential of collaboration becomes particularly evident by the example of assisted dying: it raises a wide ...
Patrick Schuchter   +3 more
wiley   +1 more source

Digitizing Dignity: Analyzing Digital Twins Through the Lens of Multidimensional Human Dignity

open access: yesBioethics, EarlyView.
ABSTRACT In precision medicine, digital twins—virtual models of patients created using personalized data and advanced machine learning—are potentially changing healthcare by predicting health outcomes and guiding medical decisions. However, their use raises complex ethical questions, particularly concerning their relationship to human dignity. Patients
Andrew J. Barnhart
wiley   +1 more source

Research of variations of ionospheric parameters during the local meteorological phenomena in the kaliningrad region

open access: yesE3S Web of Conferences, 2016
The paper presents observations of atmospheric and ionospheric parameters during strong meteorological disturbances (storms) in the Kaliningrad region. The analysis of ionospheric observations has shown that during meteorological storms the amplitude of ...
Borchevkina Olga   +5 more
doaj   +1 more source

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