Results 171 to 180 of about 355,275 (255)

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, Accepted Article.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among long‐term HCQ users with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain OCT (SD‐OCT) for screening. Methods A systematic search of PubMed, Scopus,
Narsis Daftarian   +4 more
wiley   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index (FI‐Lab) for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, Accepted Article.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical frailty index (FI).
Grace Burns   +2 more
wiley   +1 more source

Trajectories of Physical Function in Canadian Children with Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, Accepted Article.
Objectives We describe trajectories of physical function in children newly diagnosed with juvenile idiopathic arthritis (JIA) and identify trajectories with persisting functional impairments and associated baseline characteristics. Methods We included patients enrolled in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry ...
Clare Cunningham   +14 more
wiley   +1 more source

Laser Engineering of HfN‐Based Nanoparticles for Safe NIR‐I Photothermal and X‐ray Enhancing Cancer Therapies

open access: yesAdvanced Functional Materials, EarlyView.
In this study, we produced HfN‐based nanoparticles via femtosecond laser ablation in acetone. The nanoparticles exhibit a red‐shifted plasmonic resonance in the NIR‐I window, colloidal stability after coating with polyethyleneglycol, and excellent biocompatibility. The photothermal and X‐ray sensitization therapeutic effects were demonstrated for tumor
Julia S. Babkova   +15 more
wiley   +1 more source

Highly Conductive and Stretchable Photothermal CuSe Fiber for Wearable Electronics and Implantable Drug Release Systems

open access: yesAdvanced Functional Materials, EarlyView.
The conductive and stretchable photothermal CuSe fiber is fabricated for versatile biomedical applications. This CuSe fiber functions as a reliable wearable strain sensor and heater due to its high conductivity, stretchability and photothermal efficiency.
Kukro Yoon   +9 more
wiley   +1 more source

Kaplan–Meier curve

open access: yesBritish Journal of Surgery, 2017
J. Ranstam, J. Cook
semanticscholar   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji   +7 more
wiley   +1 more source

Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient‐Derived Model

open access: yesAdvanced Healthcare Materials, EarlyView.
This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti   +27 more
wiley   +1 more source

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