Results 51 to 60 of about 47,168 (211)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Kapłan wyjaśniający modlitwy i czynności liturgiczne

open access: yesRuch Biblijny i Liturgiczny, 1960
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Władysław Padacz
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Tematy rozważań Pasyjnych „Siedmiu ostatnich słów Jezusa” F.J. Sheena w audycjach radiowych „The Catholic Hour”

open access: yes, 2021
Szczególnym kontekstem głoszenia krzyża Chrystusowego są kazania pasyjne na temat ostatnich siedmiu słów Jezusa wypowiedzianych na krzyżu. Tego zadania wielokrotnie podejmował się F.J.
Surmiak, Dawid, Dawid Surmiak
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Kapłan w blasku i cieniu współczesności

open access: yesWrocławski Przegląd Teologiczny, 2010
Un’analisi sul profilo del prete nella cultura contemporanea. Il pericolo è ridursi a un funzionario che eroga servizi. Altro pericolo è “modernità liquida”: ridursi all’immagine (stavolta in senso superficiale) e al successo. Un altro pericolo: un prete
Andrzej Tomko
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Nie tylko ksiądz Marek – kapłani w Pamiątkach Soplicy Henryka Rzewuskiego [PDF]

open access: yes, 2020
The romantic noble tale is a specific literary genre, revealing the specifics of Polish Sarmatian culture, in which religiosity and a sense of community are controversial.
Bojko, Pelagia, Pelagia Bojko
core   +2 more sources

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