Results 81 to 90 of about 355,275 (255)

An Introduction to Survival Statistics: Kaplan-Meier Analysis

open access: yesJournal of the Advanced Practitioner in Oncology, 2016
Studies of how patients re¬spond to treatment over time are fundamentally impor¬tant to understanding how therapies influence quality of life and progression of disease during survivorship.
William N. Dudley,1   +2 more
semanticscholar   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Jesus Christ the High Priest

open access: yesRuch Biblijny i Liturgiczny, 2012
Study of terms connected with High Priest, both in Masoretic Text and in the LXX, gives the possibility to present the role, activity and exceptionality of High Priest. It is seen through the specific High Priest’s vestments, having particular functions.
Roman Mazur
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Entrevista con Temma Kaplan

open access: yesHistoria contemporánea, 2016
La entrevista se inicia analizando la incorporación de los estudios de género en la universidad norteamericana a partir de los años setenta. El importante desarrollo posterior fue acompañado de una intensa renovación teórica alentado sobre todo desde las
José Javier Díaz Freire
doaj   +1 more source

Religijność i wiara Górali Czadeckich zamieszkałych w Polsce na terenie gminy Brzeźnica [PDF]

open access: yes, 2005
artykuł zamieszczony w materiałach sympozjum "W kręgu relacji polsko-rumuńskich"
Seul, Sabina
core   +1 more source

Priests for a resurrected Poland : the ideas and activity of the Polish Pontifical College in Rome [PDF]

open access: yes, 2015
Papieskie Kolegium Polskie zostało założone w Rzymie w 1866 roku przez Zgromadzenie Zmartwychwstańców pod patronatem papieża Piusa IX. Powstanie tej instytucji formacji kapłańskiej miało ogromne znaczenie wobec sytuacji Kościoła i duchowieństwa w Polsce ...
Mleczko, Wojciech
core   +1 more source

Higher-order free logic and the Prior-Kaplan paradox

open access: yesCanadian Journal of Philosophy, 2016
The principle of universal instantiation plays a pivotal role both in the derivation of intensional paradoxes such as Prior’s paradox and Kaplan’s paradox and the debate between necessitism and contingentism.
A. Bacon, J. Hawthorne, G. Uzquiano
semanticscholar   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

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