Results 201 to 210 of about 156,165 (266)

MLANA is a potential prognostic biomarker and correlated with immune infiltration in skin cutaneous melanoma. [PDF]

Clin Exp Med
Tang N, Lai X, Wen W, Wu Y, Xiong X.
europepmc   +1 more source

ETV4 Promotes Colorectal Cancer Progression by Reprogramming Asparagine Metabolism to Remodel the Stromal Microenvironment

Advanced Science, EarlyView.
ETV4 coordinates a dual transcriptional program by upregulating MET and asparagine synthetase (ASNS). The resulting asparagine (Asn) secretion acts as a metabolic signal, reprogramming hepatic stellate cells (HSCs) and primary cancer‐associated fibroblasts (CAFs) toward an inflammatory phenotype. These activated stromal cells release HGF to sustain the
Dujiang Fu, Meijia Zhang, Maoping Cai, Miao Wang, Ziao Huang, Zesheng Lin, Yixin Liu, Wang Qian, Guopeng Chen, Yuxing Liang, Dongyi Wei, Jing xie, Picheng Yan, Yuanyuan Qu, Yongchang Wei   +14 more
wiley   +1 more source

A novel signature of palmitoylation for predicting prognosis and therapeutic response of hepatocellular carcinoma. [PDF]

Discov Oncol
Li Y, Yi Z, Liu L, Huang D.
europepmc   +1 more source

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

Advanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang, Chao Yang, Hua Qiu, Yuan Du, Xicheng Wang, Yuting Li, Mingyang Xu, Changcheng Liu, Xiuhua Li, Na Guo, Jun Shi, Wencheng Zhang, Zhiying He   +12 more
wiley   +1 more source

Divergent Differentiation and Histologic Subtypes in Upper Tract Urothelial Carcinoma Demonstrate Distinct Patterns of Extraurothelial Recurrence. [PDF]

Eur Urol Open Sci
Wang B, Davis LE, Nandwana D, Siva J, Maina E, Weight CJ, Haywood S, Campbell S, Campbell R, Sindhani M, Abouassaly R, Olivares R, Berglund R, Stein R, Kaouk J, Alaghehbandan R, Bukavina L.   +16 more
europepmc   +1 more source

A novel disulfidptosis-related lncRNA signature to predict prognosis and immune response of cervical cancer. [PDF]

Medicine (Baltimore)
Zhao H, Guo Y, Wang L, Li R, Wang Y.
europepmc   +1 more source

Integrated multi-dataset screening to predict prognosis and identify immunotherapy gene targets in hepatocellular carcinoma patients. [PDF]

Sci Rep
Zhou L, Zhang W, Liu Z, Xie Y, Jiang K.
europepmc   +1 more source

Glioblastoma survival in rural America: a 10-year experience from a quaternary care center. [PDF]

J Neurooncol
Pack E, Cifarelli CP, Bhatia S, Lewis J, Brandmeir N, Gleckman A, Han PC, Wages NA, Dotson TS, Denney MW, Wen S, Armistead M, Norouzi S, Aulakh S.   +13 more
europepmc   +1 more source

Construction of taurine metabolism-related risk model and subtype identification in colorectal cancer to predict prognosis and immunological features. [PDF]

J Gastrointest Oncol
Wang Q, Chen X, Zheng H, Fu J, Yuan Y.
europepmc   +1 more source