Results 241 to 250 of about 237,530 (303)

Bioprinted Tumor Microenvironment Models Reveal Immune Evasion and Guide CAR‐NK Therapeutic Strategies

Advanced Science, EarlyView.
This study presents a 3D embedded bioprinting platform that recapitulates key stromal features of the tumor microenvironment using fibroblasts and lung‐derived ECM. The model enables functional assessment of CAR‐NK cells and provides a versatile tool to support the development of next‐generation immunotherapeutic strategies against solid tumors ...
Dahong Kim, Seona Jo, In‐Hwan Jang, Yu‐Jin Kim, Youngmee Jung, Junhyoung Ahn, Hyungjun Lim, Jae Jong Lee, Kangwon Lee, Tae‐Don Kim, Su A Park   +10 more
wiley   +1 more source

Visual analytics framework for survival analysis and biomarker discovery from gene expression data. [PDF]

PLoS One
Kokošar J, Turkay C, Ausec L, Štajdohar M, Zupan B.   +4 more
europepmc   +1 more source

Biomimetic Nanoplatform for Targeted Glioblastoma Therapy via Concurrently Triggering GPX4/DHODH Mediated Ferroptosis

Advanced Science, EarlyView.
Considering the great challenge in Glioblastoma multiforme (GBM) treatment, the authors designed and synthesized a multifunctional nanoplatform that effectively induced ferroptosis by synergetically inhibiting intrinsic intrisinc anti‐ferroptosis proteins, GPX4 & DHODH, and realized excellent in vitro and in vivo anti‐GBM effect.
Guodong Ren, Xuewei Wang, Panpan Li, Hao Wu, Zhifei Bi, Qi Gao, Bolong Ma, Zixuan Tian, Jianfei Liu, Fuqiang Feng, Wen Liu, Lin Li, Chengwu Zhang   +12 more
wiley   +1 more source

Persistent Low-Grade Squamous Intraepithelial Lesions and the Risk of Overtreatment: Evidence from Long-Term Active Surveillance. [PDF]

Cancers (Basel)
Bruno MT, Pagana A, Palermo IC, Fiore M, Siena R, Lo Giudice C, Cavallaro AG, Mereu L.   +7 more
europepmc   +1 more source

Safety, Efficacy, and Intermediate‑Term Outcomes of CT‑Guided Cryoablation of T1 Renal Cell Carcinoma: A Retrospective Single‑Center Study. [PDF]

J Belg Soc Radiol
Frenoy L, Buyck PJ, Bonne L, Van Cleynenbreugel B, Albersen M, Maleux G.   +5 more
europepmc   +1 more source

Structural and Non-Structural Deterioration After Biological Aortic Valve Replacement: Long-Term Outcomes of 918 High-Risk Patients. [PDF]

J Cardiovasc Dev Dis
Hlavička J, Landgraf J, Winter A, von Zeppelin M, Ilgin Y, Salem R, Hecker F, Walther T, Holubec T.   +8 more
europepmc   +1 more source

The adverse prognostic impact of reduced chemotherapy dose intensity appears attenuated in early breast cancer patients with treatment-relevant neutropenia: a retrospective cohort study. [PDF]

Arch Gynecol Obstet
Eissler K, Engler T, Dannehl D, Schönfisch B, Englisch J, Hartkopf AD, Brucker SY, Grischke EM, Volmer LL, Englisch A.   +9 more
europepmc   +1 more source

Staged management of infected diabetic foot ulcers: a 300-patient cohort study on prognostic grading, pathogen dynamics, and individualized risk prediction. [PDF]

Front Med (Lausanne)
Zhang Y, Zhang J.
europepmc   +1 more source

Benchmarking progression-free survival ratio as primary endpoint in precision oncology clinical trials. [PDF]

NPJ Precis Oncol
Nichetti F, Hüllein J, du Rusquec P, Pleasance E, Chen L, Mock A, Horak P, Ambrosini P, Rota S, Niger M, Agnelli L, Tinè G, Edelmann D, Le Tourneau C, Laskin J, Pruneri G, Wang C, Hübschmann D, de Braud F, Fröhling S, Mariani L.   +20 more
europepmc   +1 more source