Results 91 to 100 of about 32,632 (220)

Bootstrapping the Kaplan–Meier estimator on the whole line [PDF]

Annals of the Institute of Statistical Mathematics, 2018
This article is concerned with proving the consistency of Efron's (1981) bootstrap for the Kaplan-Meier estimator on the whole support of a survival function. While other works address the asymptotic Gaussianity of the estimator itself without restricting time (e.g.
openaire   +3 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

THE RELATIONSHIP BETWEEN JOB SEEKING DURATION AND THE TIME OF UNEMPLOYMENT BENEFIT. SEARCHING THEORY ON LABOUR MARKET

Acta Universitatis Lodziensis. Folia Oeconomica, 2014
The aim of the article is to analyze the influence of time of unemployment benefit on the time of registered unemployment. In research were used a duration analysis methods (Kaplan-Meier estimator, Cox regression model).
Iwona Markowicz
doaj  

Wavelet estimation of copula function based on censored data

Journal of Inequalities and Applications, 2019
In this paper, we consider wavelet analysis to obtain an estimator of a copula function based on censored data. We show that optimal convergence rates for the mean integrated squared error (MISE) of linear wavelet-based function estimators are exact ...
Bahareh Ghanbari, Masoud Yarmohammadi, Narges Hosseinioun, Esmaeil Shirazi   +3 more
doaj   +1 more source

Displaying survival of patient groups defined by covariate paths: Extensions of the Kaplan-Meier estimator. [PDF]

Stat Med, 2021
Jay M, Betensky RA.
europepmc   +1 more source

Nearest Neighbor and Kernel Survival Analysis: Nonasymptotic Error Bounds and Strong Consistency Rates

, 2019
We establish the first nonasymptotic error bounds for Kaplan-Meier-based nearest neighbor and kernel survival probability estimators where feature vectors reside in metric spaces.
Chen, George H.
core  

Modeling the number of hidden events subject to observation delay

, 2019
This paper considers the problem of predicting the number of events that have occurred in the past, but which are not yet observed due to a delay. Such delayed events are relevant in predicting the future cost of warranties, pricing maintenance contracts,
Antonio, Katrien, Crevecoeur, Jonas, Verbelen, Roel   +2 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source