Results 131 to 140 of about 220,037 (330)

A comprehensive review of methodologies and application to use the real-world data and analytics platform TriNetX

Frontiers in Pharmacology
Randomized controlled trials (RCTs) are the gold standard for evaluating the efficacy and safety of both pharmacological and non-pharmacological interventions.
Ralf J. Ludwig, Ralf J. Ludwig, Ralf J. Ludwig, Matthew Anson, Matthew Anson, Henner Zirpel, Diamant Thaci, Henning Olbrich, Katja Bieber, Khalaf Kridin, Khalaf Kridin, Khalaf Kridin, Astrid Dempfle, Philip Curman, Philip Curman, Philip Curman, Philip Curman, Sizheng S. Zhao, Uazman Alam, Uazman Alam, Uazman Alam   +20 more
doaj   +1 more source

Censored Quantile Regression Redux [PDF]

Quantile regression for censored survival (duration) data offers a more flexible alternative to the Cox proportional hazard model for some applications. We describe three estimation methods for such applications that have been recently incorporated into ...
Roger Koenker
core   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas, Connor A. Law, Joan A. Casey, Thomas Mosley, Rebecca F. Gottesman, Ramon Diaz‐Arrastia, Holly Elser, Andrea L. C. Schneider   +7 more
wiley   +1 more source

Un análisis transversal y longitudinal en el estado de pobreza en Alemania = A cross-sectional and longitudinal analysis of poverty in Germany [PDF]

Revista de Métodos Cuantitativos para la Economía y la Empresa, 2007
El objetivo del trabajo se centra en un análisis transversal y longitudinal de la pobreza en Alemania en el período de 1985 a 1996, utilizando la base de datos Panel Comparability Project.
González Rodríguez, María Rosario, Martín Martín, Domingo, González Abril, Luis, Departamento de Economía Aplicada I. Universidad de Sevilla   +3 more
doaj  

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

Methodological biases in observational hospital studies of COVID-19 treatment effectiveness: pitfalls and potential

Frontiers in Medicine
IntroductionThis study aims to discuss and assess the impact of three prevalent methodological biases: competing risks, immortal-time bias, and confounding bias in real-world observational studies evaluating treatment effectiveness.
Oksana Martinuka, Derek Hazard, Hamid Reza Marateb, Hamid Reza Marateb, Marjan Mansourian, Marjan Mansourian, Miguel Ángel Mañanas, Miguel Ángel Mañanas, Sergio Romero, Sergio Romero, Manuel Rubio-Rivas, Martin Wolkewitz   +11 more
doaj   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Association of CDKN2A/B Homozygous Deletion and Extent of Resection With Survival of Patients With WHO CNS5 Grade 4 Astrocytoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai, Guanglin Zhu, Qiu He, Chen Luo, Lingyun Zhuo, Xingfu Wang, Yiming Chen, Xiaoyong Chen, Wendong You, Jiaheng Xu, Yuanxiang Lin, Dezhi Kang, Shuai Wu, Zanyi Wu   +13 more
wiley   +1 more source

Estimation and Model Selection of Semiparametric Multivariate Survival Functions under General Censorship [PDF]

Many models of semiparametric multivariate survival functions are characterized by nonparametric marginal survival functions and parametric copula functions, where different copulas imply different dependence structures.
Demian Pouzo, Xiaohong Chen, Yanqin Fan, Zhiliang Ying   +3 more
core