Results 141 to 150 of about 220,037 (330)
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi +8 more
wiley +1 more source
Quantile Regression Under Random Censoring [PDF]
No abstract.
Bo Honore, James L. Powell, Shakeeb Khan
core
Sex Differences in Medication Discontinuation in Axial Spondyloarthritis
Arthritis Care &Research, EarlyView.Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall +9 more
wiley +1 more source
Kaplan-Meier estimator in competing risk contexts
Hacettepe Journal of Mathematics and Statistics, 2015 Survival analysis has become in a common procedure in biomedical re-searches. Conventionally, the well-known nonparametric Kaplan-Meier(KM) estimator is used in order to approximate the real survivor curve.However, in competing risk contexts where more than one failure causecompete to occur and only one of them is of interest, the direct useof the ...
openaire +2 more sources
Arthritis Care &Research, EarlyView.Objective We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analyzed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalized with AMI between 2005 and 2019 from the Myocardial Ischaemia ...
Megan Butler +8 more
wiley +1 more source
p3state.msm: Analyzing Survival Data from an Illness-Death Model
Journal of Statistical Software, 2011 In longitudinal studies of disease, patients can experience several events across a followup period. Analysis of such studies can be successfully performed by multi-state models.
Luís Filipe Meira Machado +1 more
doaj
Deductive semiparametric estimation in Double-Sampling Designs with application to PEPFAR
, 2019 Non-ignorable dropout is common in studies with long follow-up time, and it can bias study results unless handled carefully. A double-sampling design allocates additional resources to pursue a subsample of the dropouts and find out their outcomes, which ...
Frangakis, Constantine +2 more
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Arthritis Care &Research, Accepted Article.Objective Mycophenolate Mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon due to the lower fibrotic burden and the predominance of the vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis +77 more
wiley +1 more source
Scientific ReportsIncreasing number of patients with ulcerative colitis (UC) have received biologic treatment during the last decade. The association between endoscopic healing (EH) and biologic treatment failure remains understudied.
Akira Komatsu +5 more
doaj +1 more source