Results 251 to 260 of about 18,301 (299)

PGK1 Suppresses CD8+ T Cell‐Mediated Antitumor Immunity Through CCL2/CCR2/Tumor‐Associated Macrophages Axis in Hepatocellular Carcinoma

Advanced Science, EarlyView.
PGK1 in tumor cells upregulates CCL2 expression through activation of the AKT/GSK‐3β/β‐catenin signaling axis, thereby promoting the recruitment and M2 polarization of TAMs and ultimately impairing the infiltration and activation of CD8+ T cells within the HCC tumor microenvironment. ABSTRACT Patients with advanced hepatocellular carcinoma (HCC) have a
Xi Liu, Jianpeng Liu, Zhihao Zhang, Xizhi Yu, Junjie Qian, Limin Ding, Qinchuan Wu, Zhe Yang, Xing‐Yu Luo, Xinjiang Ding, Rong Su, Xiaobo Yu, Yiting Qiao, Shengyong Yin, Haiyang Xie, Lin Zhou, Yuanxing Liu, Shusen Zheng   +17 more
wiley   +1 more source

Age and sex adjusted adiposity estimators predict all cause and pneumonia related mortality in hospitalized older patients with severe dysphagia receiving artificial nutrition. [PDF]

Front Nutr
Liu Z, Chen H, Yang J, Lu Y, Li J, Chen Z, Jin M.   +6 more
europepmc   +1 more source

Mitochondrial Carrier SLC25A13 Drives Ferroptosis Resistance and Immune Evasion via a STAT3–IFI6 Circuit in Breast Cancer

Advanced Science, EarlyView.
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu, Yuhan Tang, Yingcui Chen, Zhuoqi Zhang, Yige Lu, Xinyue Wang, Qiyuan Shi, Wenhui Zhao, Hui Pang   +8 more
wiley   +1 more source

Using Quadratic Programming to Reconstruct Data From Published Survival and Competing Risks Analyses. [PDF]

Stat Med
Titman AC.
europepmc   +1 more source

Functional limit laws for the increments of Kaplan-Meier product-limit processes and applications.

Einmahl, J.H.J., Deheuvels, P.
core  

MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes

Advanced Science, EarlyView.
A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak, Juliane Tschuck, Stefanie A. I. Weiß, Daniel Kaemena, Karolin Klimm, Ana Galhoz, Larissa Ringelstetter, Myles Fennell, Juliane Merl‐Pham, Anna Artati, Stefanie Strasser, Ralph Garippa, Michael Witting, Hans Zischka, Joel A. Schick, Stefanie M. Hauck, Michael P. Menden, Michelle Vincendeau, Brent R. Stockwell, Kamyar Hadian   +19 more
wiley   +1 more source

Survival Models for Predictive Maintenance and Remaining Useful Life in Sensor-Enabled Smart Energy Networks: A Review. [PDF]

Sensors (Basel)
Shadi MR, Mirshekali H, Tahavori M, Shaker HR.   +3 more
europepmc   +1 more source

Frailty in middle adulthood and associations with negative health-related outcomes in NHANES. [PDF]

Aging Clin Exp Res
Finamore P, Pedone C, Ekström M, Mannino DM, Incalzi RA, Scarlata S.   +5 more
europepmc   +1 more source

Predictors of True Early Recurrence in Patients Undergoing Radiofrequency Ablation for Hepatocellular Carcinoma. [PDF]

JGH Open
Yen YH, Kee KM, Hung CH, Chen CH, Hu TH, Wang JH, Lu SN.   +6 more
europepmc   +1 more source

Causal Inference Methods Based on Pseudo-Observations: A Comparative Analysis of Treatment Types for Iranian Gastrointestinal Cancer Patients. [PDF]

Asian Pac J Cancer Prev
Varnaseri S, Hesam S, Seyedtabib M.
europepmc   +1 more source