Results 41 to 50 of about 220,037 (330)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Bandwidth Selection Problem for Nonparametric Regression Model with Right-Censored Data [PDF]

Revista Română de Statistică, 2017
In this paper, the proposed estimator for the unknown nonparametric regression function is a Nadarya-Watson (Nadarya, 1964; Watson, 1964) type kernel estimator. In this estimation procedure, the censored observations are replaced by synthetic data points
Dursun AYDIN, Ersin YILMAZ
doaj  

Estimating the Survival Distribution for Right-Censored Data with Delayed Ascertainment [PDF]

, 2012
In many clinical trials, patients are not followed continuously. This means their vital status may not be immediately recorded. In such cases, the results from the Kaplan-Meier estimator or the log rank test, popular methods used for survival analysis ...
Kim, Eun-Jin
core  

Semiparametric inference for the recurrent event process by means of a single-index model [PDF]

, 2014
In this paper, we introduce new parametric and semiparametric regression techniques for a recurrent event process subject to random right censoring. We develop models for the cumula- tive mean function and provide asymptotically normal estimators.
Bouaziz, Olivier, Geffray, Ségolen, Lopez, Olivier   +2 more
core   +5 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

The importance of selecting Bayesian nonparametric survival models: application to the estimation of unemployment durations

المجلة الدولية للأداء الاقتصادي, 2023
The Kaplan-Meier and Fleming-Harrington estimator in the frequentist approach are functional methods. We compare in this article the different Bayesian structures of the Kaplan-Meier and Fleming-Harrington estimators through the information deviance ...
Ahmed HAMIMES
doaj  

Examining Selected Theoretical Distributions of Life Expectancy to Analyse Customer Loyalty Durability. The Case of a European Retail Bank

Acta Universitatis Lodziensis. Folia Oeconomica, 2020
One of the key elements related to calculating Customer Lifetime Value is to estimate the duration of a client’s relationship with a bank in the future. This can be done using survival analysis.
Dominik Kubacki, Robert Kubacki
doaj   +1 more source

Methods for Improving the Variance Estimator of the Kaplan–Meier Survival Function, When There Is No, Moderate and Heavy Censoring-Applied in Oncological Datasets

Frontiers in Public Health, 2022
In case of heavy and even moderate censoring, a common problem with the Greenwood and Peto variance estimators of the Kaplan–Meier survival function is that they can underestimate the true variance in the left and right tails of the survival distribution.
Habib Nawaz Khan, Qamruz Zaman, Fatima Azmi, Gulap Shahzada, Mihajlo Jakovljevic, Mihajlo Jakovljevic, Mihajlo Jakovljevic   +6 more
doaj   +1 more source

Crude Cumulative Incidence in the form of a Horvitz-Thompson like and Kaplan-Meier like Estimator [PDF]

, 2006
The link between the nonparametric estimator of the crude cumulative incidence of a competing risk and the Kaplan-Meier estimator is exploited. The equivalence of the nonparametric crude cumulative incidence to an inverse-probability-of-censoring ...
Antolini, Laura, Biganzoli, Elia Mario, Boracchi, Patrizia   +2 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source