Estimador de Kaplan-Meier na avaliação do tempo de conclusão do Profmat/UFSJ
A presença de dados incompletos ou censuras no conjunto de dados requer técnicas estatísticas especializadas para acomodar a informação contida nessas observações, tais como a Análise de Sobrevivência.
Roberta Cristina Ferreira Arvelos +1 more
doaj +1 more source
Nonparametric survival analysis of epidemic data
This paper develops nonparametric methods for the survival analysis of epidemic data based on contact intervals. The contact interval from person i to person j is the time between the onset of infectiousness in i and infectious contact from i to j, where
Aalen +38 more
core +1 more source
Brainstem metastases treated with Gamma Knife stereotactic radiosurgery: the Indiana University Health experience [PDF]
Brainstem metastases offer a unique challenge in cancer treatment, yet stereotactic radiosurgery (SRS) has proven to be an effective modality in treating these tumors.
Ansari, Shaheryar +9 more
core +2 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Inferences for current chronic graft-versus-host-disease free and relapse free survival
This paper provides the methodologies of a new summary curve that measures the dynamic outcome following allogenic hematopoietic cell transplantation.
Xu Zhang +2 more
doaj +1 more source
Turnbull versus Kaplan-Meier estimators of cure rate estimation using interval censored data [PDF]
This study deals with the analysis of the cure rate estimation based on the Bounded Cumulative Hazard (BCH) model using interval censored data, given that the exact distribution of the data set is unknown.
Abu Bakar, Mohd Rizam +2 more
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Prostate cancer treatment with Irreversible Electroporation (IRE): Safety, efficacy and clinical experience in 471 treatments. [PDF]
BackgroundIrreversible Electroporation (IRE) is a novel image-guided tissue ablation technology that induces cell death via very short but strong pulsed electric fields.
Guenther, E +6 more
core +2 more sources
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source

