Results 41 to 50 of about 26,219 (238)

Kaposi’s sarcoma with the eyelid involvement (6 clinical cases)

Alʹmanah Kliničeskoj Mediciny, 2018
Kaposi's sarcoma is a multifocal tumor from vascular endothelium with a low grade of malignancy. It develops due to underlying immune deficiency and is associated with human herpesvirus 8. Kaposi's sarcoma of the eyelids is rare, and its diagnosis can be
E. E. Grishina
doaj   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

Effectiveness of community‐based hypertension management on hypertension in the urban slums of Haiti: A mixed methods study

The Journal of Clinical Hypertension
Hypertension is a leading contributor to mortality in low‐middle income countries including Haiti, yet only 13% achieve blood pressure (BP) control.
Reichling St Sauveur, Rodney Sufra, Marie Christine Jean Pierre, Vanessa Rouzier, Fabiola Preval, Serfine Exantus, Mirline Jean, Josette Jean, Guyrlaine Pierre‐Louise Forestal, Obed Fleurijean, Nour Mourra, Anju Ogyu, Rodolphe Malebranche, Jean Pierre Brisma, Marie M. Deschamps, Jean W. Pape, Radhika Sundararajan, Margaret L. McNairy, Lily D. Yan   +18 more
doaj   +1 more source

Immune reconstitution inflammatory syndrome associated with acquired immunodeficiency syndrome-related gastrointestinal limited Kaposi's sarcoma presenting as acute intestinal obstruction: a case report

Journal of Medical Case Reports, 2011
Introduction Immune reconstitution inflammatory syndrome during anti-retroviral treatment of acquired immunodeficiency syndrome (AIDS) -associated gastrointestinal Kaposi's sarcoma has rarely been reported.
Pathak Hari, Shrivastav Ankit, Pal Jyotirmoy, Sarkar Dipendra   +3 more
doaj   +1 more source

Kaposi's sarcoma in two primary liver allograft recipients occurring under FK506 immunosuppression [PDF]

, 1993
Of 1463 liver allograft recipients receiving the combination of FK506 and steroids as their primary immunosuppressive regimen, 2 patients developed Kaposi's sarcoma.
Bronsther, O, Fung, JJ, Kadry, Z, Randhawa, P, Starzl, TE, Van Thiel, DH   +5 more
core  

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

Advanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño, Víctor M. de la Oliva Roque, Javier‐Ignacio Ramirez‐Lopez, David P. Kreil, Joaquín Dopazo, Carlos Loucera   +5 more
wiley   +1 more source

Utilising proteomic approaches to understand oncogenic human herpesviruses [PDF]

, 2014
The γ‑herpesviruses Epstein-Barr virus and Kaposi's sarcoma‑associated herpesvirus are successful pathogens, each infecting a large proportion of the human population.
Baquero-Perez, B, Berndt, A, Hughes, DJ, Jackson, BR, Owen, CB, Schumann, S, Whitehouse, A   +6 more
core   +1 more source

The HCMV‐encoded miR‐UL36‐3p promotes angiogenesis of endothelial cells by downregulating FOXO3

Animal Models and Experimental Medicine, EarlyView.
This illustration shows the role of hcmv‐miR‐UL36‐3p in endothelial cell angiogenesis. During productive infection, endothelial cells express HCMV‐encoded miRNAs. Viral hcmv‐miR‐UL36‐3p promotes endothelial cell proliferation, migration, and capillary tube formation by directly targeting and downregulating FOXO3. The pro‐angiogenic activity of hcmv‐miR‐
Chen Wang, Mengyu Li, Guosheng Li, Hao Zhang, Cheng Wang, Chen‐Yu Zhang   +5 more
wiley   +1 more source

Kaposi’s sarcoma associated with chronic myeloid leukemia and imatinib mesylate therapy

Clinical Case Reports, 2022
Kaposi's sarcoma is associated with immunosuppression and human herpesvirus 8 infection, while rarely described in myeloid malignancies. Here, we illustrate a rare case of chronic myeloid leukemia treated with imatinib, a tyrosine kinase inhibitor, who ...
Matteo D’Addona, Luca Pezzullo, Valentina Giudice, Bianca Serio, Carlo Baldi, Pio Zeppa, Carmine Selleri   +6 more
doaj   +1 more source

Cultured Kaposi's sarcoma tumor cells exhibit a chemokine receptor repertoire that does not allow infection by HIV-1 [PDF]

, 2001
SCOPUS: ar.jinfo:eu-repo/semantics ...
Thierry Simonart, Claire Debussher, Corinne Liesnard, Laurent Debaisieux, Marie-Luce Delforge, Aurore de Lavareille, Philippe Hermans, Jean-Paul Van Vooren, Patrick Stordeur, V Fiorelli, Y Chang, RC Gallo, K Murakami-Mori, B Ensoli, GD Kelly, P Delli Bovi, SE Mahoney, EE Kaaya, Y Lunardi-Iskandar, YQ Huang, BJ Nickoloff, S Uccini, T Simonart, AV Moses, RW Doms, Y Feng, A Borsetti, R Benelli, D Blankaert, T Simonart, AM Vandamme, K Van Laethem, DJ Dairaghi, SK Gupta, S Lee, M Stürlz   +35 more
core   +1 more source