Results 41 to 50 of about 14,149 (169)

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li, Xudong Hu, Chenxing Yang, Na Liu, Lin Wang, Xi Cai, Min Tang, Ya Cao, Li Shang, Feng Shi   +9 more
wiley   +1 more source

Immune reconstitution inflammatory syndrome associated with acquired immunodeficiency syndrome-related gastrointestinal limited Kaposi's sarcoma presenting as acute intestinal obstruction: a case report

Journal of Medical Case Reports, 2011
Introduction Immune reconstitution inflammatory syndrome during anti-retroviral treatment of acquired immunodeficiency syndrome (AIDS) -associated gastrointestinal Kaposi's sarcoma has rarely been reported.
Pathak Hari, Shrivastav Ankit, Pal Jyotirmoy, Sarkar Dipendra   +3 more
doaj   +1 more source

Diagnostic Usefulness of Cell Block Samples in Fluid Overload‐Associated Large B‐Cell Lymphoma

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fluid overload‐associated B‐cell lymphoma (FO‐LBCL) is a B‐cell neoplasm that presents as serous effusions without detectable tumor masses and Kaposi sarcoma‐associated herpesvirus (KSHV)/human herpesvirus 8 (HHV8) infection. Here, we report a case of an 81‐year‐old female patient with FO‐LBCL (Stage IVA) who presented with pericardial and ...
Hiroyuki Okanishi, Hiroko Kuwabara, Hiroko Nakayama, Mayo Odaka, Kozue Ariga, Isako Kataoka, Mari Tomiuka, Mayumi Uragami, Chihiro Deguchi, Shizuka Ono, Reika Takeda, Yoshitaka Kurisu, Yoshinobu Hirose, Yuuki Kinoshita, Taiji Yokote   +14 more
wiley   +1 more source

Clinical and laboratory characteristics, staging, and outcomes of individuals with AIDS-associated Kaposi's sarcoma at an university hospital [PDF]

Anais Brasileiros de Dermatologia, 2017
: Background: Kaposi's sarcoma continues to be the most common human immunodeficiency virus - associated neoplasm with considerable morbidity and mortality.
Catarina Tenório de Lima, Paulo Sérgio Ramos de Araújo, Heberton Medeiros de Teixeira, Josemir Belo dos Santos, Vera Magalhães da Silveira   +4 more
doaj   +1 more source

Cutaneous Leiomyosarcoma of the Head and Neck: Appreciation of a More Indolent Biological Behavior and Implications for Its Management

Head &Neck, EarlyView.
ABSTRACT Background Leiomysosarcoma (LMS) is generally associated with high metastatic potential and poor survival. Cutaneous LMS (cLMS) has been considered a different entity with more indolent biological behavior. Methods A narrative review was performed to assess the biological behavior of cLMS, with special attention for the head and neck location.
Eelco de Bree, Remco de Bree, Carlos Chiesa‐Estomba, Orlando Guntinas‐Lichius, M. P. Sreeram, Dimosthenis Michelakis, Karthik N. Rao, Alessandra Rinaldo, Alfio Ferlito   +8 more
wiley   +1 more source

Improvements in Blood Pressure Control and the Hypertension Care Continuum Over 2 Years in Urban Haiti Amidst Civil Unrest

The Journal of Clinical Hypertension
Hypertension (HTN) is the leading cause of death worldwide, yet only 8% of individuals have controlled blood pressure (BP) in low‐ and middle‐income countries, with particular challenges in humanitarian crisis settings including Haiti.
Miranda Metz, Rodney Sufra, Anju Ogyu, Vanessa Rouzier, Reichling St. Sauveur, Kelly Celestin, Guyrlaine Forrestal, Fabyola Preval, Mirline Jean, Suzanne Edwidge Marcelin, Auguste Sarine, Catherine Bennett, Serena Koenig, Kenneth Jamerson, Jean William Pape, Lily D. Yan, Margaret L. McNairy   +16 more
doaj   +1 more source

Non–AIDS‐Defining Cancer Incidence in People With HIV in Milan, Italy, 2000–2023: Temporal Trends and Comparison With the General Population

International Journal of Cancer, EarlyView.
ABSTRACT People with HIV (PWH) are living longer, but contemporary data on non–AIDS‐defining cancers (NADCs) in Italy remain limited. We assessed incident cancers in a retrospective cohort of PWH in Milan, Italy, between January 2000 and December 2023. Follow‐up was grouped into 2000–2007, 2008–2015, and 2016–2023. Incidence rates (IRs) were calculated
Giacomo Pozza, Maddalena Matone, Letizia Oreni, Giorgia Carrozzo, Beatrice Caloni, Maria Vittoria Cossu, Davide Moschese, Anna Lisa Ridolfo, Cristina Gervasoni, Cinzia Fasola, Nicla La Verde, Davide Dalu, Spinello Antinori, Andrea Gori, Andrea Giacomelli   +14 more
wiley   +1 more source

Kaposi’s sarcoma associated with chronic myeloid leukemia and imatinib mesylate therapy

Clinical Case Reports, 2022
Kaposi's sarcoma is associated with immunosuppression and human herpesvirus 8 infection, while rarely described in myeloid malignancies. Here, we illustrate a rare case of chronic myeloid leukemia treated with imatinib, a tyrosine kinase inhibitor, who ...
Matteo D’Addona, Luca Pezzullo, Valentina Giudice, Bianca Serio, Carlo Baldi, Pio Zeppa, Carmine Selleri   +6 more
doaj   +1 more source

The Africa We Want: A Perspective on the African Code Against Cancer To Be Developed for Sub‐Saharan Africa

International Journal of Cancer, EarlyView.
ABSTRACT Sub‐Saharan Africa (SSA) faces a unique cancer burden, characterized by a disproportionately high mortality‐to‐incidence ratio, a large share of infection‐related cancers, and distinct environmental exposures. Implementation of national policies on primary prevention is limited, and public literacy regarding cancer risk and curability remains ...
Anthony Kityo, Phyllis Ohene‐Agyei, Felix M. Onyije, Hannah Simba, Annet Nakaganda, Denis Chopera, Kofi Mensah Nyarko, Benido Impouma, Mary Nyangasi, Blandina Mmbaga, Valerie McCormack, Cesaltina Lorenzoni, Miriam Mutebi, Joachim Schüz, Carolina Espina   +14 more
wiley   +1 more source

Familial Kaposi’s Sarcoma: A Report of Five Cases from Greece

Case Reports in Dermatological Medicine, 2014
Introduction. Familial cases of Kaposi’s sarcoma have rarely been reported. Kaposi’s sarcoma is not uncommon in Greece; its incidence is estimated at 0.20 per 100.000 habitants, showing an increased predominance in the Peloponnese, in Southern Greece ...
Kalliopi Armyra, Anargyros Kouris, Arsinoi Xanthinaki, Alexandros Stratigos, Irene Potouridou   +4 more
doaj   +1 more source