Results 91 to 100 of about 203,949 (292)
Expert Perspective: Diagnosis and Treatment of Castleman Disease
Arthritis &Rheumatology, Accepted Article.Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen +2 more
wiley +1 more source
A case of patch stage of Kaposi’s sarcoma and discussion of the differential diagnosis
Rare Tumors, 2016 A 55-year-old HIV positive male had a skin lesion biopsy which showed atypical vascular proliferation within the superficial and deep dermis with mild atypia of lining endothelial cells.
Ipshita Kak +4 more
doaj +1 more source
PLoS ONE, 2008 Both Kaposi's sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) are members of the human gamma herpesvirus family: each is associated with various human cancers. The majority of AIDS-associated primary effusion lymphoma (PEL) are co-infected with both KSHV and EBV.
Jiang, Yanjun +3 more
openaire +5 more sources
Approaches to repurposing reverse transcriptase antivirals in cancer
British Journal of Clinical Pharmacology, EarlyView.This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head +2 more
wiley +1 more source
Case Reports in Radiology, 2015 Kaposi’s sarcoma was originally described by Moritz Kaposi in 1872 as a rare form of multiple hemorrhagic skin lesions. Today it is well documented as a systemic, multifocal, steadily progressive reticuloendothelial system tumor with a predilection for ...
Jaydeep Halankar +2 more
doaj +1 more source
Kaposi´s sarcoma of the larynx: an unusual location in a HIV-negative patient case report
The Pan African Medical Journal, 2020 Head and neck involvement of Kaposi’s sarcoma is rarely encountered, especially for the Mediterranean classic subtype. Here we report a case of non-AIDS related laryngeal Kaposi’s sarcoma in a 77-year-old Tunisian man complaining of 4-month history of ...
Zeineb Naimi +5 more
doaj +1 more source
Journal of Clinical Oncology, 2016 Purpose Kaposi's sarcoma (KS) is a multicentric tumor caused by Kaposi's sarcoma-associated herpesvirus. Unmet needs include therapies that are oral, anthracycline sparing, and deliverable in resource-limited settings.
M. Polizzotto +15 more
semanticscholar +1 more source
Journal of General Virology, 2010 Kaposi's sarcoma-associated herpesvirus (KSHV) infection goes through latent and lytic phases, which are controlled by the viral replication and transcription activator (RTA). Upon KSHV infection, the host responds by suppressing RTA-activated lytic gene expression through interferon regulatory factor 7 (IRF-7), a key regulator of host innate immune ...
Li Zhang +8 more
openaire +3 more sources
ChemBioChem, Accepted Article.Fibroblast growth factor 2 (FGF2) regulates signal transduction by forming complexes with its receptors, FGF receptors (FGFRs), and heparan sulfate (HS), playing a crucial role in biological systems. Although HS has been suggested to modulate FGF/FGFR signaling as a co‐receptor, multiple hypotheses exist regarding how HS affects FGF/FGFR signaling, and
Yuga Okada +5 more
wiley +1 more source
Retention in Care among HIV-Infected Pregnant Women in Haiti with PMTCT Option B
AIDS Research and Treatment, 2016 Background. Preventing mother-to-child transmission of HIV relies on engagement in care during the prenatal, peripartum, and postpartum periods. Under PMTCT Option B, pregnant women with elevated CD4 counts are provided with antiretroviral prophylaxis ...
Jodie Dionne-Odom +10 more
doaj +1 more source