Results 101 to 110 of about 203,949 (292)

Treating loss-to-follow-up as a missing data problem: a case study using a longitudinal cohort of HIV-infected patients in Haiti

open access: yesBMC Public Health, 2018
Background HIV programs are often assessed by the proportion of patients who are alive and retained in care; however some patients are categorized as lost to follow-up (LTF) and have unknown vital status.
Deanna P. Jannat-Khah   +6 more
doaj   +1 more source

Kaposi Sarcoma, a Trifecta of Pathogenic Mechanisms

open access: yesDiagnostics, 2022
Kaposi’s sarcoma is a rare disease with four known variants: classic, epidemic, endemic and iatrogenic (transplant-related), all caused by an oncogenic virus named Human Herpes Virus 8.
Gabriela Rusu-Zota   +5 more
doaj   +1 more source

The zinc finger DNA-binding domain of K-RBP plays an important role in regulating Kaposi's sarcoma-associated herpesvirus RTA-mediated gene expression

open access: yesVirology, 2009
K-RBP is a KRAB-containing zinc finger protein with multiple zinc finger motifs and represses Kaposi's sarcoma-associated herpesvirus (KSHV) transactivator RTA-mediated transactivation of several viral lytic gene promoters, including the ORF57 promoter.
Yang, Zhilong   +3 more
openaire   +3 more sources

Investigating the mechanisms of capsicum in age‐related hearing loss: Based on network pharmacology

open access: yesEye &ENT Research, EarlyView.
Abstract Background To explore the material basis and action mechanism of the chemical component gene of pepper on presbycusis, and to provide a reference for the traditional Chinese medicine treatment of age‐related hearing loss (ARHL). Methods The chemical composition and action targets of traditional Chinese medicine flavor of pepper were searched ...
Yan Wang   +9 more
wiley   +1 more source

Sarcoma de Kaposi asociado a no VIH: A propósito de un caso

open access: yesGalicia Clínica, 2022
Kaposi sarcoma (KS), first described in 1872, is a angioproliferative neoplasm that often presents with red-purple macules in the skin. This report is of a case of classic/iatrogenic form of KS in a 79-year-old male, that had a prolonged hospitalization ...
Joana Fontes   +3 more
doaj   +1 more source

Plaque‐Like Dermatofibroma: A Case Report and a Review of the Literature With a Focus on Dermoscopy

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Plaque‐like dermatofibroma (PLDF) is a rare clinical variant of dermatofibroma (DF), characterised by flat, infiltrative lesions, often larger than 50 mm in diameter and located on the trunk or lower extremities. A 44‐year‐old male presented to our clinic with a 20 cm brownish plaque with peripheral satellite lesions on the right antecubital ...
Francesco Cavallo   +7 more
wiley   +1 more source

Mapping protein–protein interactions by mass spectrometry

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu   +4 more
wiley   +1 more source

Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy [PDF]

open access: yes, 2017
KSHV and EBV are gammaherpesviruses strictly linked to human cancers. Even if the majority of cancer cells harbor a latent infection, the few cells that undergo viral replication may contribute to the pathogenesis and maintenance of the virus-associated ...
Cirone, Mara   +7 more
core   +2 more sources

An Update on Kaposi’s Sarcoma: Epidemiology, Pathogenesis and Treatment

open access: yesDermatologic Therapy, 2016
Kaposi’s sarcoma is an angioproliferative neoplasm which has undergone considerable epidemiologic change since the original description by Moritz Kaposi in the late 1800s.
P. Curtiss   +2 more
semanticscholar   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro   +5 more
wiley   +1 more source

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