Targeting of Prosurvival Pathways as Therapeutic Approaches against Primary Effusion Lymphomas: Past, Present, and Future [PDF]
, 2015 Constitutively activated prosurvival pathways render cancer cells addicted to their effects. Consequently they turn out to be the Achilles’ heels whose inhibition can be exploited in anticancer therapy.
CIRONE, Mara +6 more
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Kaposi sarcoma of th e penis in anHIV-negative patient
Einstein (São Paulo)Kaposi sarcoma is an angioproliferative disorder that ranges from a single indolent skin lesion to respiratory and gastrointestinal/visceral involvement. Kaposi sarcoma is rare in non-immunosuppressed patients.
José Francisco Aguilar Guevara +5 more
doaj +1 more source
The zebrafish xenograft platform-A novel tool for modeling KSHV-associated diseases [PDF]
, 2019 Kaposi\u27s sarcoma associated-herpesvirus (KSHV, also known as human herpesvirus-8) is a gammaherpesvirus that establishes life-long infection in human B lymphocytes.
Berman, Jason N +12 more
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SAGE Open Medical Case ReportsAngiosarcoma-like Kaposi sarcoma represents a recently delineated rare histomorphologic variant of Kaposi sarcoma that can be difficult to distinguish from other vasoproliferative lesions. Conventional lesions of Kaposi sarcoma encompass patches, plaques,
Jasmine Gill +3 more
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Penile Kaposi sarcoma: A case of complete resolution with highly active antiretroviral therapy alone [PDF]
, 2011 Kaposi sarcoma remains an important cause of morbidity in HIV-infected patients. Regardless of the recent pharmacological progress, treatment of this malignancy is still disappointing.
Alves, R. +6 more
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HIV-1 Evolutionary Patterns Associated with Metastatic Kaposi's Sarcoma during AIDS. [PDF]
, 2016 Kaposi's sarcoma (KS) in HIV-infected individuals can have a wide range of clinical outcomes, from indolent skin tumors to a life-threatening visceral cancer. KS tumors contain endothelial-related cells and inflammatory cells that may be HIV-infected. In
Barbier, Andrew E +6 more
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Diagnostic dilemma in Kaposi’s sarcoma
Indian Journal of Plastic Surgery, 2006 Kaposi′s sarcoma is described as cutaneous and extracutaneous neoplasm predominantly affecting older individuals. Though earlier uncommon and endemic to certain African areas, its incidence is on a rise due to infections with human immunodeficiency virus
Rao B.S Satish +4 more
doaj +1 more source
Discovery of Kaposi’s sarcoma herpesvirus-encoded circular RNAs and a human antiviral circular RNA
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Human herpesviruses are known to interact with non-protein encoding RNAs like microRNAs and long noncoding RNAs. Circular RNAs (circRNAs) are recently discovered noncoding RNAs that are long-lived and resistant to exonucleases, and that bind
Takanobu Tagawa +10 more
semanticscholar +1 more source
Remembering the forgotten child: the role of immune checkpoint inhibition in patients with human immunod eficiency virus and cancer. [PDF]
, 2019 Patients with human immunodeficiency virus (HIV) infection have a high risk of developing virally-mediated cancers. These tumors have several features that could make them vulnerable to immune checkpoint inhibitors (ICIs) including, but not limited to ...
Adashek, Jacob J +3 more
core
Risk factors for high anti-HHV-8 antibody titers (≥1:51,200) in black, HIV-1 negative South African cancer patients: a case control study [PDF]
, 2003 Background: Infection with human herpesvirus 8 (HHV-8) is the necessary causal agent in the development of Kaposi's sarcoma (KS). Infection with HIV-1, male gender and older age all increase risk for KS.
BM Friedman +51 more
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