Results 71 to 80 of about 42,270 (264)

Differential regulation of translational stress responses by herpesvirus ubiquitin deconjugases

The FEBS Journal, EarlyView.
Translating viral mRNAs is challenging due to structural features that may slow translation or induce ribosome stalling. The viral ubiquitin deconjugases encoded by human pathogenic herpesviruses regulate the cellular response to ribosomal stress by inhibiting various branches of the Ribosomal Quality Control (RQC) and activating Ribosomal Stress ...
Jiangnan Liu, Noemi Nagy, Carlos Mario Ayala‐Torres, Maria G. Masucci   +3 more
wiley   +1 more source

Ultrasound findings in Kaposi sarcoma patients: overlapping sonographic features with disseminated tuberculosis [PDF]

, 2023
Michaela Aurelia Maria Huson, Tapiwa Kumwenda, Joe Gumulira, Ethel Rambiki, Claudia Wallrauch, Tom Heller   +5 more
openalex   +1 more source

Late diagnosis of paediatric HIV infection in high‐income countries: Lessons from the HIV Perinatal Virtual Clinic

HIV Medicine, EarlyView.
Abstract Introduction Timely diagnosis of HIV in children remains a challenge in all settings including low‐prevalence, high‐income countries (HIC). We aimed to characterize the prevalence of late diagnosis, and prior missed diagnostic opportunities among new presentations of paediatric HIV in HIC referred to an international Perinatal Virtual Clinic ...
Carolina Curto, M. Tritzali, A. Bamford, A. C. Bailey, E. G. H. Lyall, N. E. Mackie, N. Tickner, C. Foster, on behalf of the PVC   +8 more
wiley   +1 more source

Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy [PDF]

, 2017
KSHV and EBV are gammaherpesviruses strictly linked to human cancers. Even if the majority of cancer cells harbor a latent infection, the few cells that undergo viral replication may contribute to the pathogenesis and maintenance of the virus-associated ...
Cirone, Mara, Faggioni, Alberto, Gilardini Montani, Maria Saveria, Gonnella, Roberta, Granato, Marisa, Romeo, Maria Anele, Santarelli, Roberta, Tiano, Mariangela Sara   +7 more
core   +2 more sources

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

Journal of Internal Medicine, EarlyView.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron, Jennifer S. Lin, Mark I. Ryder, Peter Bergman   +3 more
wiley   +1 more source

Sarcoma de Kaposi Anoperineal: uma Rara Apresentação

Clinical and Biomedical Research, 2022
O sarcoma de Kaposi é uma neoplasia maligna associada à infecção pelo herpes vírus humano 8 em doentes imunossupressos. O sarcoma de Kaposi Epidêmico é o tipo epidemiológico mais frequente e afeta indivíduos VIH-positivos.
Patrícia Motta Lima, Caroline Lorenzoni Ghezzi, Tiago Leal Ghezzi   +2 more
doaj  

Kaposi Sarcoma mimicking pedal osteomyelitis in a patient with HIV

Radiology Case Reports, 2019
Kaposi Sarcoma (KS) is an angio-proliferative mesenchymal neoplasm that typically affects the skin. In the setting of AIDS, it is usually disseminated, commonly involving noncutaneous sites like oral cavity, lymph nodes, pulmonary, and gastrointestinal ...
Swati Sharma, MD, Chandana Kurra, MD, Marsela Hyska-Campbell, DO, Kristin Taylor, MD, Mauricio Hernandez, PhD, Christine Palma, DPM, Ahmad Alkhasawneh, MD, Paul Wasserman, DO   +7 more
doaj   +1 more source

Herpesvirus Simplex Virus‐1 Exploits Inflammation to Infect Periodontal Stem Cells and Disrupt Lineage Commitment

Journal of Periodontal Research, EarlyView.
HSV‐1 infects oral mesenchymal stem cells both in vitro and in vivo to dysregulate their lineage commitment. An inflamed gingival environment increases susceptibility to HSV‐1 infection, which further elevates proinflammatory cytokine levels and exacerbates alveolar bone loss.
Araceli Valverde, Raza Ali Naqvi, Yinghua Chen, Alireza Moshaverinia, Anne George, Deepak Shukla, Gloria Martinez, Gabriella Chapa, Salvador Nares, Afsar R. Naqvi   +9 more
wiley   +1 more source

Risk factors for high anti-HHV-8 antibody titers (≥1:51,200) in black, HIV-1 negative South African cancer patients: a case control study [PDF]

, 2003
Background: Infection with human herpesvirus 8 (HHV-8) is the necessary causal agent in the development of Kaposi's sarcoma (KS). Infection with HIV-1, male gender and older age all increase risk for KS.
BM Friedman, C Boshoff, C Boshoff, D Serraino, D Whitby, DH Kedes, Dimitra Bourboulia, EP Zorrilla, F Sitas, F Vitale, Freddy Sitas, G de-The, G de-The, G Rezza, GR Simpson, H Renwick, J Iscovich, J Ziegler, Janet M Wojcicki, JJ Goedert, JL Ziegler, JL Ziegler, KA Staskus, L Rainbow, Lara Stein, LD Baker, M Dedicoat, Margaret I Urban, Martin Hale, Moosa Patel, P Cook-Mozaffari, P Kellam, Paul Ruff, PS Moore, R Greenblatt, R Newton, R Newton, R Tedeschi, Ranjan Sur, RJ Biggar, Rob Newton, RP Stowe, S Lemeshow, S Plancoulaine, SJ Gao, STATA, Statistics South Africa, TH Bothwell, TH Bothwell, VR Gordeuk, Y Chang, Z Grossman   +51 more
core   +2 more sources

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source