Results 41 to 50 of about 458 (179)

Artificial intelligence strategies for predicting kinase inhibitor resistance: A comprehensive review of methods, challenges, and future perspectives

open access: yesJournal of Intelligent Medicine, EarlyView.
Abstract Kinase inhibitors are essential in targeted cancer therapy, yet resistance often emerges through secondary mutations, activation of compensatory signaling pathways, or drug‐efflux mechanisms. Artificial intelligence (AI) provides a workflow‐based strategy rather than a list of unrelated tools for predicting and addressing kinase‐inhibitor ...
Faris Hassan   +3 more
wiley   +1 more source

Effects of genotype and environment on the physiochemical properties of Canadian oat varieties

open access: yesJournal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 3111-3121, 30 March 2025.
Abstract BACKGROUND The relationship between oat grain composition and physical attributes as influenced by oat genotype and Canadian growing environments was investigated. Thirty Canadian oat (Avena sativa L.) genotypes, grown in three Canadian growing locations (Brandon, Manitoba; Portage la Prairie, Manitoba; and Lacombe, Alberta) over 2 consecutive
Vanessa Alexander   +4 more
wiley   +1 more source

Systemic Absorption and Pharmacokinetics of Five Novel Topical Dermatologic Agents: A Review

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT In recent years, innovative topical medications with novel mechanisms of action have emerged to treat common dermatologic conditions such as acne, atopic dermatitis, vitiligo, and actinic keratoses. These molecularly targeted therapies offer improved safety and tolerability compared to traditional options like corticosteroids.
Mary Dyson   +4 more
wiley   +1 more source

Relationships between acoustic scattering layers and ocean stratification: An acoustic approach to estimate mixed layer depth

open access: yesLimnology and Oceanography: Methods, EarlyView.
Abstract Ocean stratification, measured as mixed layer depth (MLD), is an important feature that influences many processes in the ocean; for example, by mediating the fluxes of momentum, heat and crucially key gases such as CO2 and oxygen from the atmosphere into the water column and vice versa. The conventional methods to measure stratification (e.g.,
Fabio Campanella   +2 more
wiley   +1 more source

The jubilees calendar in practice [PDF]

open access: yes, 2010
The names of the months corresponding to December in the Gothic calendar – jiuleis, in the English calendar as described by Bede – Giuli, and in the Old Icelandic semester-reckoning (misseristal) calendar – Ýlir, are cognates.
Landau, David
core   +2 more sources

Development of a moored radium in situ sampler to measure annual time series

open access: yesLimnology and Oceanography: Methods, EarlyView.
Abstract Radium is a useful tracer of sediment‐derived materials, improving our understanding of the geochemical cycling of elements at ocean boundaries. We have developed an autonomous in situ sampler to collect time series samples of radium isotopes on mooring deployments.
Lauren Kipp   +5 more
wiley   +1 more source

Karaites & Reformers: Two Failed Cases of Coherent Interpretation [PDF]

open access: yes, 2022
There are two groups which claim that proper textual interpretation does not require extratextual information. They posit that the meaning of texts is discoverable from the words of the text and/or an individual\u27s reason alone.
Roberts, Menashe Chaim
core   +1 more source

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source

Evaluating Large Language Model Adherence to Targeted Fifth‐Grade Readability Standards in Patient Education on Chronic Conditions

open access: yes
Chronic Diseases and Translational Medicine, EarlyView.
Faheed Shafau   +3 more
wiley   +1 more source

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