Results 141 to 150 of about 84,325 (261)
Low diagnostic yield of presurgical genetic testing in adult patients with epilepsy
Epilepsia, EarlyView.Abstract Objective
To determine the diagnostic yield of genetic testing in patients undergoing presurgical evaluation for epilepsy. Methods
We conducted a cohort study including 115 adult patients who underwent presurgical evaluation in the Calgary Epilepsy Program between 2019 and 2023 and who had undergone research exome sequencing.Clara Jünemann, Amanda Stuart, Navprabhjot Kaur, Samuel Wiebe, Nathalie Jette, Shaily Singh, Felippe Borlot, Susanne Knake, The Calgary Comprehensive Epilepsy Program Collaborators, Paolo Federico, Colin Josephson, William Murphy, Andrea Salmon, Guillermo Delgado Garcia, Walter Hader, Ping Yee Billie Au, Karl Martin Klein +16 morewiley +1 more sourceWhere Are We Now? Benchmarking Large Language Models (LLMs) in Computed Tomography (CT)-Based Detection of Intracranial Hemorrhage. [PDF]
CureusWu AQ, Davis P, Gajjar AA, Patel S, Sollenberger C, Hoglund Z, Ghanta P, Jabarkheel R, Scott KW, Catapano JS, Burkhardt JK, Srinivasan VM. +11 moreeuropepmc +1 more sourceA translational multimodal machine‐learning prototype predicting valproate response in epilepsy treatment
Epilepsia, EarlyView.Abstract Objective
Epilepsy affects ~1% of the global population and often requires lifelong antiseizure medication (ASM) therapy. Valproic acid (VPA) is a commonly prescribed first‐line ASM, yet only approximately half of patients achieve sustained seizure freedom. Treatment selection remains largely empirical.Simeon Platte, Afsheen Kumar, Giorgia Guerini, Massimo Pandolfo, Denise Haslinger, Colin B. Josephson, Guillermo Delgado‐García, Navprabhjot Kaur, Michaela‐Pauline Lux, Heiko Stempfle, Chantal Depondt, Reetta Kälviäinen, Felix Rosenow, Sophie von Brauchitsch, Karl Martin Klein, Andreas G. Chiocchetti +15 morewiley +1 more sourcePediatric epilepsy surgery: Global survey of referral and presurgical evaluation practices
Epilepsia, EarlyView.Abstract Objective
Pediatric epilepsy surgery is well established, but contemporary global data on referral and presurgical evaluation practices are lacking. This International League Against Epilepsy (ILAE) Pediatric Epilepsy Surgery Task Force study provides an updated overview of current trends and regional differences. Methods
Group‐level data were Georgia Ramantani, J. Helen Cross, Dorottya Cserpan, Emtnan Ahemad, Javier Aparicio, Alexis Arzimanoglou, Carmen Barba, William Bingaman, Kees Braun, Richard J. Burman, James Butler, Lixin Cai, Dezhi Cao, Roberto Caraballo, Mathilde Chipaux‐Raffo, Thomas Cloppenborg, Arthur Cukiert, Cristine Mella Cukiert, Sameer Dal, Dario Englot, Noelle Enright, Aria Fallah, Sarah Ferrand Sorbets, Martha Feucht, Deepak Gill, Laura Guio Mahecha, Aris Hadjinicolaou, Tove Hallböök, A. Simon Harvey, Hans Holthausen, Yuwu Jiang, Lakshminarayanan Kannan, Kalman A. Katlowitz, Katarzyna Kotulska‐Jóźwiak, Martin Kudr, Matt Lallas, Ahsan Moosa Naduvil Valappil, Sandeep Bhagwan Patil, Tom Pieper, Nicola Specchio, Manjari Tripathi, Lejla Vendegh, Howard Weiner, Jo Wilmshurst, Mary Lou Smith, Elaine Wirrell, ILAE Pediatric Epilepsy Surgery Task Force and Study Group, Fabrice Bartolomei, Juan Carlos Benedetti Isaac, Poodipedi Sarat Chandra, Mary Connoly, Daniel Curry, Vicki Deli‐Peri, Luca De Palma, Nabeel Diab, Petia Dimova, Carolina Munoz Castro, Georg Dorfmüller, Jana Domínguez, Gianluca D'Onofrio, Christin Eltze, Johannes M. Nico Enslin, András Fogarasi, Siby Gopinath, Renzo Guerrini, Giulia Nobile, Masaki Iwasaki, Sita Jayalakshmi, Takayuki Kikuchi, Noritsugu Kunihiro, Paweł Kowalczyk, Niklaus Krayenbühl, Pavel Kršek, Thilo Kalbhenn, Kensuke Kawai, Cassia Maniquis, Wim Otte, María Ángeles Pérez‐Jiménez, Juan Carlos Pérez‐Poveda, Catherine Riney, Jonathan Roth, Sabine Rona, Karl Rössler, Olga Teo, Oana Tarta Arsene, Laura Tassi, Hartlieb Till, T S Dhanya, Catalina Soto Órdenes, Piradee Suwanpakdee, Steffen Syrbe, Nigel Peter Symss, Jay Shetty, Dilşad Türkdoğan, Takehiro Uda, Naotaka Usui, Vrajesh Udani, Jithangi Wanigasinghe, Yi Wang +98 morewiley +1 more sourcePediatric epilepsy surgery: Global survey of invasive explorations
Epilepsia, EarlyView.Abstract Objective
Invasive presurgical evaluation plays a key role in pediatric epilepsy surgery, particularly in magnetic resonance imaging (MRI)‐negative cases, by guiding resective, disconnective, or ablative procedures. This International League Against Epilepsy (ILAE) Pediatric Epilepsy Surgery Taskforce study provides an updated global overview ...Georgia Ramantani, Martha Feucht, Dorottya Cserpan, Javier Aparicio, Alexis Arzimanoglou, Fabrice Bartolomei, William Bingaman, Kees P. J. Braun, Richard J. Burman, Dezhi Cao, Roberto Caraballo, Mathilde Chipaux‐Raffo, Thomas Cloppenborg, J. Helen Cross, Arthur Cukiert, Cristine Mella Cukiert, Daniel J. Curry, Luca De Palma, Petia Dimova, Christin Eltze, Dario J. Englot, Johannes M. Nico Enslin, Aria Fallah, Stefano Francione, Deepak Gill, Tove Hallböök, A. Simon Harvey, Hans Holthausen, Sita Jayalakshmi, Yuwu Jiang, Lakshminarayanan Kannan, Matt Lallas, Sandeep Bhagwan Patil, María Ángeles Pérez‐Jiménez, Juan Carlos Pérez‐Poveda, Tom Pieper, Sabine Rona, Victoria San Antonio‐Arce, Jay Shetty, Mary Lou Smith, Piradee Suwanpakdee, Oana Tarta Arsene, Laura Tassi, Martin Tisdall, Manjari Tripathi, Ahsan Moosa Naduvil Valappil, Howard Weiner, Elaine Wirrell, Lixin Cai, Sarah Ferrand‐Sorbets, ILAE Pediatric Epilepsy Surgery Taskforce and Study Group, Carmen Barba, Marcelo Budke, James Butler, Poodipedi Sarat Chandra, Mary Connoly, Sameer Dal, Georg Dorfmüller, Noelle Enright, Siby Gopinath, Aris Hadjinicolaou, Masaki Iwasaki, Thilo Kalbhenn, Kalman A. Katlowitz, Kensuke Kawai, Takayuki Kikuchi, Katarzyna Kotulska‐Jóźwiak, Niklaus Krayenbühl, Martin Kudr, Noritsugu Kunihiro, Cassia Maniquis, Ailsa McLellan, Carolina Munoz Castro, Lino Nobili, Wim Otte, Manas Panigrahi, Veronica Pelliccia, Karl Rössler, Siraruj Sakoolnamarka, Didier Scavarda, Catalina Soto Órdenes, Nicola Specchio, Nigel Peter Symss, TS Dhanya, Olga Teo, Hartlieb Till, Dilşad Türkdoğan, Takehiro Uda, Vrajesh Udani, Shimrit Uliel‐Sibony, Naotaka Usui, Carlos Valera, Lejla Vendegh, Yi Wang, Jithangi Wanigasinghe, Jo Wilmshurst, Oscar Zorro Guio +96 morewiley +1 more sourceRemifentanil Versus Rocuronium for Optimising Video Laryngoscopy Assisted Tracheal Intubation-The ROCVIDEO Trial Protocol. [PDF]
Acta Anaesthesiol ScandIpsen EØ, Lundstrøm LH, Lodenius Å, Fisker G, Hovind MF, Nielsen CL, Oskarsdottir H, Strøm C, Rosenstock CV, Madsen KPD, Wichmann S, Afshari A, Andersen JH, Nedergaard HK, Bill L, Cronhjort M, Mathiesen O, Jakobsen JC, Vested M, Nørskov AK. +19 moreeuropepmc +1 more sourceProgress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development
Epilepsia, EarlyView.Abstract
This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell +7 morewiley +1 more sourceToward a biopsy-free approach: cardiac magnetic resonance T1 mapping for detecting heart transplant rejection. [PDF]
Eur Heart J Cardiovasc ImagingTaipale M, Pentikäinen M, Martelius L, Mutka A, Kytölä S, Kankainen M, Peltonen JI, Syrjälä S, Lahtiharju A, Lommi J, Jahnukainen T, Lemström K, Ojala T. +12 moreeuropepmc +1 more source
