, 2013 Data are summarized in the table (above) and refer to 30 analyzed mitoses for each sample. Three abnormal karyotypes are shown (below). N = normal karyotype; n.d. = not determined.
Julia Wenegrat +8 more
openaire +2 more sources
Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns [PDF]
, 2021 Central to tumor evolution is the generation of genetic diversity. However, the extent and patterns by which de novo karyotype alterations emerge and propagate within human tumors are not well understood, especially at single-cell resolution.
Christopher Kimberley +25 more
core +1 more source
Proceedings of the National Academy of Sciences, 2002 Alterations in the genetic content of a cell are the underlying cause of many human diseases, including cancers. We have developed a method, called digital karyotyping, that provides quantitative analysis of DNA copy number at high resolution. This approach involves the isolation and enumeration of short sequence tags from specific genomic loci ...
Tian-Li, Wang +6 more
openaire +2 more sources
Inflammatory Cytokines in Maternal Circulation and Placenta of Chromosomally Abnormal First Trimester Miscarriages [PDF]
, 2012 The impact of abnormal placental karyotype on the inflammatory response within the villous tissue and peripheral circulation of women with miscarriage was evaluated.
Jean Calleja-Agius +5 more
core +1 more source
Zoo-FISH in the European mole (Talpa europaea) detects all ancestral Boreo-Eutherian human homologous chromosome associations [PDF]
, 2006 Zoo-FISH with human whole-chromosome paint probes delineated syntenic association of human homologous chromosome segments 3-21, 14-15, 16-19, 4-8, 7-16 and 12-22 (twice) in the European mole (Talpa europaea, Talpidae, Eulipotyphla, Mammalia).
Müller, Stefan, Volleth, M.
core +1 more source
Somatic chromosome counts and karyomorphological analysis of 12 Allium (Amaryllidaceae) taxa
Journal of Asia-Pacific Biodiversity, 2023 The genus Allium is a well-known model system for cytological research, and its cytological characteristics are considered important for species identification.
Yeseul Kim +6 more
doaj +1 more source
Changing Trends over the Years in Pregnancy Termination due to Fetal Anomalies
İstanbul Medical Journal, 2021 Introduction:To examine the indications for termination due to fetal anomalies performed in our clinic between January 2015 and October 2020 and to determine the differences between years.Methods:This study is a retrospective, observational study ...
Miraç Özalp +6 more
doaj +1 more source
Long-term cultivation of two diploid epithelial cell lines derived from normal rat liver cells [PDF]
, 1974 To obtain a useful rat liver cell line for in vitro carcinogenesis, two rat diploid epithelial cell lines were established from a 7-day-old male rat by the repeated colonial clone method.
Nakabayashi, Hidekazu +2 more
core +1 more source
Androgen Insensitivity Syndrome: A Rare Cause of Primary Amenorrhoea [PDF]
Journal of Clinical and Diagnostic ResearchAndrogen Insensitivity Syndrome (AIS) is a rare X-linked Disorder of Sexual Differentiation (DSD) caused by a mutation in the Androgen Receptor (AR) gene, which is located on the X chromosome (Xq11-q12).
Madhulima Saha +4 more
doaj +1 more source
The Karyotype of Blainville's Beaked Whale, Mesoplodon densirostris
, 2020 The karyotype of the Odontocete whale, Mesoplodon densirostris, has not been previously reported. The chromosome number is determined to be 2n = 42, and the karyotype is presented using G-, C-, and nucleolar organizer region (NOR) banding.
Finlayson, Kimberly +2 more
core +1 more source