Results 61 to 70 of about 77,988 (331)

NF2 is Essential for Human Endoderm Development

open access: yesAdvanced Science, EarlyView.
This study demonstrates that NF2, moesin‐ezrin‐radixin like (MERLIN) tumor suppressor (NF2) is essential for human endoderm formation. NF2 knockout human induced pluripotent stem cells fail to form endoderm both in vitro and in vivo due to yes‐associated protein 1 (YAP1) nuclear translocation, redirecting differentiation toward myofibroblast‐like cells.
Minjin Jeong   +5 more
wiley   +1 more source

Karyotype analysis in Chaerophyllum cicutaria Vill. with special emphasis on satellited chromosomes

open access: yesActa Societatis Botanicorum Poloniae, 2014
Karyological studies were carried out on plants of Chaerophyllum cicutaria (Umbelliferae), which came from both lowland and montane natural populations. The chromosome number in all the examined plants was 2n = 22 and their karyotypes, though similar in ...
Włodzimierz Chojnacki   +1 more
doaj   +1 more source

Prenatal diagnosis of trisomy 6q25.3-qter and monosomy 10q26.12-qter by array CGH in a fetus with an apparently normal karyotype. [PDF]

open access: yes, 2014
We present the prenatal case of a 12.5-Mb duplication involving 6q25-qter and a 12.2-Mb deletion encompassing 10q26-qter diagnosed by aCGH, while conventional karyotype showed normal results.
Marinescu, Ponnila S   +4 more
core   +1 more source

The Hypoxia‐Associated High‐Risk Cell Subpopulation Distinctly Enhances the Progression of Glioma

open access: yesAdvanced Science, EarlyView.
This study suggests the potential roles of a novel hypoxia‐associated CDC20+KIF20A+PTTG1+ cell subpopulation in glioma progression. This high‐risk glioma cell subpopulation is therapeutically vulnerable to glioma progression and may play important roles in glioma standard‐of‐care therapeutic resistance.
Quan Wan   +13 more
wiley   +1 more source

Shifts in Chromosome Evolution Rates Shape the Karyotype Patterns of Leafcutting Ants

open access: yesEcology and Evolution
Trait evolution has become a central focus in evolutionary biology, with phylogenetic comparative methods offering a framework to study how and why traits vary among species. Identifying variations in trait evolution rates within phylogenies is important
Danon Clemes Cardoso   +1 more
doaj   +1 more source

Interphase fluorescence in situ hybridization assisting in prenatal counseling for amniocentesis karyotyping-detected fetal mosaicism

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2015
Objective: To evaluate how interphase fluorescence in situ hybridization (FISH) played a role in genetic counseling when encountering prenatally detected fetal mosaicism cases. Materials and methods: We retrospectively reviewed 17 cases of amniotic fluid
Sheng-Yuan Su   +5 more
doaj   +1 more source

Zoo-FISH in the European mole (Talpa europaea) detects all ancestral Boreo-Eutherian human homologous chromosome associations [PDF]

open access: yes, 2006
Zoo-FISH with human whole-chromosome paint probes delineated syntenic association of human homologous chromosome segments 3-21, 14-15, 16-19, 4-8, 7-16 and 12-22 (twice) in the European mole (Talpa europaea, Talpidae, Eulipotyphla, Mammalia).
Jimenez R   +5 more
core   +1 more source

Mitigating Cellular Dysfunction Through Contaminant Reduction in Synthetic circRNA for High‐Efficiency mRNA‐Based Cell Reprogramming

open access: yesAdvanced Science, EarlyView.
This study addresses the challenges of synthetic circular RNAimpurities that trigger immune responses and hinder efficacy. Key immunogenic byproducts are identified and develop a multi‐step purification process that produces ultra‐pure circRNA and enhances yields by over 10‐fold.
Ziwei Zhang   +7 more
wiley   +1 more source

Mechanisms underlying synergism between circularized tumor necrosis factor‐related apoptosis inducing ligand and bortezomib in bortezomib‐sensitive or ‐resistant myeloma cells

open access: yesHematological Oncology, Volume 40, Issue 5, Page 999-1008, December 2022., 2022
Abstract Mechanisms underlying interactions between a novel, clinically relevant circularized tumor necrosis factor‐related apoptosis inducing ligand (TRAIL) agonist, circularly permuted TRAIL (CPT) have been examined in multiple myeloma (MM) cells sensitive or resistant to bortezomib (BTZ).
Yun Leng   +11 more
wiley   +1 more source

Karyotypic description of four species of Trigona (Jurine, 1807) (Hymenoptera, Apidae, Meliponini) from the State of Mato Grosso, Brazil

open access: yesGenetics and Molecular Biology, 2004
The genus Trigona contains at least 31 species, but there have been few cytogenetic studies of this group. In this work, four species of Trigona (T. branneri, T. chanchamayoensis, T. hyalinata, and T.
Kleber França Costa   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy