Results 81 to 90 of about 77,988 (331)
A Robust Framework of Chromosome Straightening with ViT-Patch GAN [PDF]
arXiv, 2022 Chromosomes carry the genetic information of humans. They exhibit non-rigid and non-articulated nature with varying degrees of curvature. Chromosome straightening is an important step for subsequent karyotype construction, pathological diagnosis and cytogenetic map development.
arxiv
Visualizing dimensionality reduction of systems biology data [PDF]
Data Mining and Knowledge Discovery Vol 10 (1), 2012, 2012 One of the challenges in analyzing high-dimensional expression data is the detection of important biological signals. A common approach is to apply a dimension reduction method, such as principal component analysis. Typically, after application of such a method the data is projected and visualized in the new coordinate system, using scatter plots or ...
arxiv +1 more source
de novo variant calling identifies cancer mutation signatures in the 1000 Genomes Project
Human Mutation, Volume 43, Issue 12, Page 1979-1993, December 2022., 2022 Abstract Detection of de novo variants (DNVs) is critical for studies of disease‐related variation and mutation rates. To accelerate DNV calling, we developed a graphics processing units‐based workflow. We applied our workflow to whole‐genome sequencing data from three parent‐child sequenced cohorts including the Simons Simplex Collection (SSC), Simons
Jeffrey K. Ng +16 more
wiley +1 more source
Gayana: Botanica, 2010 The karyotype of Chaetanthera linearis var. linearis from Chile was examined. The species has 2n = 2x = 22 chromosomes, with 9m + 1st + 1 st-sat chromosomes. The reported karyotype is symmetric (AsK % = 58.0, TF % = 42.0 and Syi % = 72.4).
Carlos M Baeza +3 more
doaj
Induction of chromosome damage by ultraviolet light and caffeine: Correlation of cytogenetic evaluation and flow karyotype [PDF]
, 1982 Asynchrononously growing cells of a M3-1 Chinese hamster line were ultraviolet (UV) irradiated ( = 254 nm) with UV fluences up to 7.5 J/m2. After irradiation, cells were incubated with or without 2 mM caffeine for 20 hr, then mitotic cells were selected ...
Carrano +20 more
core +1 more source
Using Orientation to Distinguish Overlapping Chromosomes [PDF]
arXiv, 2022 A difficult step in the process of karyotyping is segmenting chromosomes that touch or overlap. In an attempt to automate the process, previous studies turned to Deep Learning methods, with some formulating the task as a semantic segmentation problem. These models treat separate chromosome instances as semantic classes, which we show to be problematic,
arxiv
TrAp: a Tree Approach for Fingerprinting Subclonal Tumor Composition [PDF]
Nucl. Acids Res. 41 (2013) e165, 2013 Revealing the clonal composition of a single tumor is essential for identifying cell subpopulations with metastatic potential in primary tumors or with resistance to therapies in metastatic tumors. Sequencing technologies provide an overview of an aggregate of numerous cells, rather than subclonal-specific quantification of aberrations such as single ...
arxiv +1 more source
American Journal of Hematology, EarlyView.ABSTRACT Adults with acute lymphoblastic leukemia/lymphoblastic lymphoma (ALL/LBL) have poorer outcomes than pediatric patients. The aim of this systematic literature review and meta‐analysis was to compare asparaginase (ASP)‐containing pediatric‐inspired regimens (PIRs) with hyper‐fractionated cyclophosphamide, vincristine, doxorubicin, and ...
Wenqing Su +5 more
wiley +1 more source
Karyotypic Study of Male Predaceous Spear-headed Katydid (Palaeoagraeciabrunnea) and Male Bluish-green Rice Grasshopper (Hieroglyphus banian) in Northern Thailand [PDF]
Warasan Witthayasat Lae Theknoloyi Mahawitthayalai Mahasarakham, 2020 Karyotypic and idiogram studies were preformed using male predaceous spear-headed katydid, Palaeoagraecia brunnea (Ingrisch, 1998), and male bluish-green rice grasshopper, Hieroglyphus banian (Fabricius, 1798), collected from Lamphun and Chiang Mai ...
Isara Patawang
doaj
Caryologia, 2023 Sotol (Dasylirion cedrosanum Trel.) is a perennial species with numerous grayish-to-green leaves that grow symmetrically from the base of the stem outward.
Catalina García +3 more
doaj +1 more source