Results 111 to 120 of about 19,041 (213)

Integrated Molecular Autopsy in a Highly Consanguineous Perinatal Cohort With Severe Malformations and Strong Genetic Susceptibility

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield of integrated molecular autopsy (IMA) by combining deep post‐mortem phenotyping with exome (ES) and targeted genome sequencing (GS) for prenatally detected anomalies. Method This retrospective study evaluated 28 perinatal cases (22 fetuses, six neonates) with severe anomalies, normal first‐tier ...
Sihem Darouich, Samia Darouich, Ahmed Khemiri, Dorsaf Gtari, Raoudha Smiti, Ahmed Nhili, Houda Bellamine   +6 more
wiley   +1 more source

Cytotaxonomy of Gallinula melanops (Gruiformes, Rallidae): Karyotype evolution and phylogenetic inference. [PDF]

Genet Mol Biol, 2021
Furo IO, Kretschmer R, O'Brien PCM, Pereira JCDC, Gunski RJ, Garnero ADV, O'Connor RE, Griffin DK, Ferguson-Smith MA, Oliveira EHC.   +9 more
europepmc   +1 more source

Bortezomib‐based chemotherapy in Chinese pediatric patients with relapsed/refractory acute lymphoblastic leukemia: A single‐center retrospective study

Pediatric Investigation, EarlyView.
Bortezomib‐based chemotherapy achieved an 88.9% remission rate in Chinese pediatric patients with relapsed/refractory B‐cell acute lymphoblastic leukemia, enabling 62.5% of responders to bridge to transplantation, while T‐cell acute lymphoblastic leukemia showed no response.
Xingyu Zhao, Jian Wang, Liping Que, Dunhua Zhou, Jianpei Fang, Luhong Xu   +5 more
wiley   +1 more source

Comparative Cytogenetics Analysis Among Peckoltia Species (Siluriformes, Loricariidae): Insights on Karyotype Evolution and Biogeography in the Amazon Region. [PDF]

Front Genet, 2021
Santos da Silva K, de Souza ACP, Pety AM, Noronha RCR, Vicari MR, Pieczarka JC, Nagamachi CY.   +6 more
europepmc   +1 more source

Human Prostate Cell Lines: Derivation, Molecular Characteristics and Appropriate Use

The Prostate, EarlyView.
ABSTRACT Background Research on prostate cancer and benign prostatic hyperplasia depends on a small number of immortalized human cell lines established between 1977 and 2001, most of them from advanced metastatic disease. The cell lines differ from one another in androgen receptor status, prostate‐specific antigen secretion, p53 status, karyotype and ...
Hamza Abohamra, Keenau Mark Pearce
wiley   +1 more source

Chromosomal rearrangements: tempo and mode of karyotype evolution in Scarabaeoidea. [PDF]

J Evol Biol
Chien S, Blackmon H.
europepmc   +1 more source

A Uterus‐Preserving Laparoscopic Technique for Cervicovaginal Agenesis With Functional Uterine Remnants

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Cervicovaginal agenesis with functional uterine remnants is a rare Müllerian anomaly that may cause obstructed menstrual flow, pelvic pain, haematometra, haematosalpinx and endometriosis. Uterus‐preserving reconstruction is challenging because it requires both neovaginal creation and durable uterine drainage.
Kiper Aslan, Isil Kasapoglu, Bahadir Kosan, Gürkan Uncu   +3 more
wiley   +1 more source

Karyotype evolution of multiple myeloma. [PDF]

J Clin Exp Hematop
Matsumoto Y, Ichimura T, Harukawa J, Fujioka K, Suzuki H, Nonaka K, Muramatsu A, Sugitani M, Kobayashi T, Iwai T, Uchiyama H.   +10 more
europepmc   +1 more source

Russian wheat aphid: a model for genomic plasticity and a challenge to breeders

Insect Science, EarlyView.
Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn, Vicky L. Tolmay, Marlon‐Schylor Luke le Roux, Lintle Mohase, Mpho S. Mafa, Vittorio F. Nicolis, Eduard Venter, Nicolaas Francois Visser Burger, Anna‐Maria Botha   +8 more
wiley   +1 more source

Karyotype Evolution and Genomic Organization of Repetitive DNAs in the Saffron Finch, <i>Sicalis flaveola</i> (Passeriformes, Aves). [PDF]

Animals (Basel), 2021
Kretschmer R, Rodrigues BS, Barcellos SA, Costa AL, Cioffi MB, Garnero ADV, Gunski RJ, de Oliveira EHC, Griffin DK.   +8 more
europepmc   +1 more source