Results 71 to 80 of about 42,553 (305)

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

Advanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang, David W. McKellar, Andrew Kowalczewski, Nhu Y. Mai, Meng Chai, Xiaojun L. Lian, Yi Zheng, Jeffrey Amack, Nathan Tucker, Iwijn De Vlaminck, Huaxiao Yang, Benjamin D. Cosgrove, Zhen Ma   +12 more
wiley   +1 more source

Reconstruction of karyotypic evolution in Saccharum spontaneum species by comparative oligo-FISH mapping

BMC Plant Biology, 2022
Background Karyotype dynamics driven by chromosomal rearrangements has long been considered as a fundamental question in the evolutionary genetics.
Zhuang Meng, Fei Wang, Quanliang Xie, Rong Li, Haitao Shen, Hongbin Li   +5 more
doaj   +1 more source

Genomic characterisation of Arachis porphyrocalyx (Valls & C.E. Simpson, 2005) (Leguminosae): Multiple origin of Arachis species with x = 9 [PDF]

, 2017
The genus Arachis Linnaeus, 1753 comprises four species with x = 9, three belong to the section Arachis: Arachis praecox (Krapov. W.C. Greg. & Valls, 1994), Arachis palustris (Krapov. W.C. Greg. & Valls, 1994) and Arachis decora (Krapov. W.C.
Lavia, Graciela Inés, Ortiz, Alejandra Marcela, Robledo Dobladez, Germán Ariel, Silvestri, María Celeste, Valls, José Francisco M.   +4 more
core   +3 more sources

An Open‐Source Pipeline for Calcium Imaging and All‐Optical Physiology in Human Stem Cell‐Derived Neurons

Advanced Science, EarlyView.
This work introduces an open‐source all‐optical platform for functional phenotyping of human stem cell‐derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and analysis to resolve single‐cell and network activity, enabling longitudinal measurements, disease modeling, and pharmacological screening in preclinical ...
Wardiya Afshar‐Saber, Federico M. Gasparoli, Ziqin Yang, Nicole A. Teaney, Rachel Hobson, Lahin Lalani, Gayathri Srinivasan, Dosh Whye, Ranit Karmakar, Elizabeth D. Buttermore, Kellen D. Winden, Cidi Chen, Mustafa Sahin   +12 more
wiley   +1 more source

Impact of temperature on karyotype differences in Cynodon dactylon of different ploidy levels at different latitudes

BMC Plant Biology
Background Chromosomal karyotype is closely linked to species evolution, adaptability, and environmental responses. As global climate change intensifies, temperature fluctuations critically affect chromosomal behavior, consequently influencing plant ...
Liwen Wang, Jingxue Zhang, Mengli Han, Chen Chen, Minghui Chen, Xuebing Yan   +5 more
doaj   +1 more source

THE PECULIARITIES OF CARIOTYPIC EVOLUTION OF MAMMALIS IN THE CAUCASUS MOUNTAINS

Юг России: экология, развитие, 2014
. In the present work chromosomal polymorphism is studied on the basis or cariotypes analisis of more than 100 species and intraspecific forms of Mammalia of the Caucasus. Divergence of branches on the phylogenetic trees received on different chromosomal
R. I. Dzuev, A. R. Dzuev
doaj   +1 more source

In silico karyotyping of chromosomally polymorphic malaria mosquitoes in the Anopheles gambiae complex [PDF]

, 2019
Chromosomal inversion polymorphisms play an important role in adaptation to environmental heterogeneities. For mosquito species in the Anopheles gambiae complex that are significant vectors of human malaria, paracentric inversion polymorphisms are ...
Besansky, N. J., Caputo, B., Della Torre, A., Love, R. R., Petrarca, V., Pombi, M., Redmond, S. N., The Anopheles gambiae1000 Genomes, Consortium   +7 more
core   +1 more source

Clinical, Genetic, and Pathologic Variability in Myelodysplastic Syndromes and Precursor Conditions Across Race, Ethnicity, and Sex

American Journal of Hematology, EarlyView.
ABSTRACT The epidemiology of myelodysplastic syndromes/neoplasms (MDS) is challenging to define due to inconsistent reporting, complex diagnostic procedures, and evolving diagnostic criteria. Using the National MDS Natural History Study—a prospective cohort with centrally adjudicated histopathology and genetic variant review—we characterized the ...
Nancy Gillis, Christelle Colin‐Leitzinger, Yi‐Han Tang, Michael Otterstatter, Seth Sherman, Ling Zhang, Lynn C. Moscinski, Mary Ellen Walker, Jeffrey S. Painter, Gregory A. Abel, Tareq Al Baghdadi, H. Joachim Deeg, James M. Foran, Steven D. Gore, Alexandra M. Harrington, Steven H. Kroft, Jane Jijun Liu, Wael Saber, Shamsuddin Virani, Rafael Bejar, R. Coleman Lindsley, Eric Padron, Matthew J. Walter, Rami Komrojki, Amy E. DeZern, Mikkael A. Sekeres   +25 more
wiley   +1 more source

Cytogenetic risk stratification in chronic myelomonocytic leukemia

Haematologica, 2011
Background The prognostic value of cytogenetic findings in chronic myelomonocytic leukemia is unclear. Our purpose was to evaluate the independent prognostic impact of cytogenetic abnormalities in a large series of patients with chronic myelomonocytic ...
Esperanza Such, José Cervera, Dolors Costa, Francesc Solé, Teresa Vallespí, Elisa Luño, Rosa Collado, María J. Calasanz, Jesús M. Hernández-Rivas, Juan C. Cigudosa, Benet Nomdedeu, Mar Mallo, Felix Carbonell, Javier Bueno, María T. Ardanaz, Fernando Ramos, Mar Tormo, Reyes Sancho-Tello, Consuelo del Cañizo, Valle Gómez, Victor Marco, Blanca Xicoy, Santiago Bonanad, Carmen Pedro, Teresa Bernal, Guillermo F. Sanz   +25 more
doaj   +1 more source

Mammalian karyotype evolution [PDF]

, 2009
Kariotip neke jedinke se odnosi na broj, veličinu i izgled njezinih kromosoma. Kromosomi pojedinih vrsta predstavljaju širok spektar raznolikosti, od broja do njihove morfologije.
Jurković, Sven
core   +2 more sources